A short video by Aaron Hartman, MD discussing links between estrogen loss in menopause and increased risk of Alzheimer's disease. He cites studies linking early menopause and anesthesia exposure, and describes how severe nocturnal hot flashes and cortisol/HPA-axis dysregulation may contribute; he recommends hormone regulation (bioidentical, nutritional, stress reduction, sleep) as brain-protective strategies.
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Not having estrogen increases your risk for Alzheimer's disease. Well, that's what this article talks about and I'll actually put a link to the original article from Pedmed in the bio section. But we've known for years that going through general anesthesia for women going through early menopause actually is associated with an increased risk for Alzheimer's disease. Now severe hot flashes, especially when you're sleeping at night, we now know can be associated with an increased risk for Alzheimer's. But why is that? Has to do with a lot of things. One of the cortisol regulation issues between your HPA axis, which is part of your brain that regulates hormones and the effect of cortisol on that. So when you drop your hormones down through menopause, if your cortisol levels are high, you're more prone to flashing phenomena because of dysregulation in that regulatory part of your brain. So regulating your hormones in menopause, whether it's bioidentical, whether it's natural nutritional, whether it's stress reduction, better sleep, a whole host of things now are important for brain.