Aaron Hartman presents the hormone hierarchy, a pyramid with the stress-response HPA axis at the top, thyroid as the metabolic engine in the middle, and sex hormones plus insulin at the base. He argues chronic stress dysfunction affects most patients far more than primary adrenal disease, and that 80% of core physiology is shared across people.
Chapters
So when learning about this, it was like, this makes sense. And then seeing how much it influences the body, it's like, why is this not the center of what we do? What kind of is this? And the gut collectively make up of. Make up the core of everything that we do in just about every patient. And then everything else around that. The 20% is kind of individualized. So without further ado, the hormone hierarchy is a pyramid, the way that I visualize it, and that the apex is the HPA axis. So the stress loop, as we describe it, some people say adrenals, but I don't want to mislead and think that this is an inherent adrenal problem. It's. It's more a dysfunction in the loop. Chronic stress, loss of resilience, flattened curves, things that we're going to talk about. And then in the middle is the thyroid, which is just kind of like the engine that runs it. The thyroid's affecting metabolism and weight and energy and mood and mindset and all these other things. And then at the bottom is sex hormones, and in there is also insulin receptors as a hormone and metabolism.