The Gut Microbiome & Metabolism Connection

So what we've come to realize is the gut microbiome is a huge, huge play with our metabolism, obesity, insulin sensitivity. But how can that be? How can our gut bacteria, our microbiome, be so intricately connected with our metabolism? GLP1 is kind of what it comes down to the glucagon, like peptide 1 is a peptide our body makes that controls metabolism, satiety, insulin sensitivity, insulin production. It's an interesting molecule because now we have weight loss drugs. These originally were diabetes medications, but we found out surreptitiously that they actually lowered people's risk for heart disease as well as obesity. What's really, really cool is that our gut makes these in response to molecules made by bacteria in our GI tract. So that's the connection between antibiotics, bacteria, and the metabolism.