Ben GreenfieldFounder, Ben Greenfield Life

Dr. John Lieurance's Road to Recovery Post-Leg Amputation

2 May 2025 · 1 min

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This YouTube interview (uploaded by Ben Greenfield, May 2, 2025) features Dr. John Lieurance discussing methylene blue — claiming neuroprotective and antimicrobial benefits and that it enhances mitochondrial function (reports all four mitochondrial complexes increase on average ~30%). He also recounts a severe injury that caused rhabdomyolysis, resulting in kidney failure requiring dialysis and a medical recommendation that he might need hip-level leg amputation.

Questions this video answers

About 30% on average.

Dialysis.

Amputation at the hip.

Chapters

When you look at the research with, with methylene blue, it's just incredible. I mean, everything from neuroprotection to it's got antimicrobial effects. It enhances the mitochondria in a way that no other molecule has been shown, where it's like all four of the complexes within the mitochondria are increased on an average, about 30%. How close did you get to anything like amputation or life threatening sepsis or anything like that? Because, I mean, from the photos I saw, it was, it was a significant injury. Well, I had kidney failure, so that I went on dialysis, and they were telling me that I would probably be on dialysis for the rest of my life. They also were telling me I'd need to have my leg amputated at the hip because I had a lot of damage, what's called rhabdomyolysis, which is death of muscle throughout my whole hip and leg.