Health Influencer Gets Custom Longevity Protocol Built From His Blood Test

The face of longevity medicine, regenerative therapy, even peptides is rapidly evolving. And you're about to see a deep dive into something called Neo7, which involves testing your organ systems, seeing what's declining, seeing what's good, and then addressing those with a customized protocol. I haven't ever done a video about this, so this is all brand new. Enjoy. All right. I'm at Austin Regenerative Therapy. You guys always have some cool cutting-edge things I've never heard of before. Uh, with Dr. Khan Nguyen. And Khan, uh, if you have been following the podcast for a while, is a multi-time podcast guest and have done some crazy things here at our clinic, including, uh, probably most well known for the plasma replacement therapy. But last time I was here, you took my blood and urine. That's right, the blood and the pee. And you told me that you have this protocol called Neo—

Neo7.

Neo7. And you want to explain it to me. And this is some cool— it's kind of like peptide-related science, right? All right. So let's do this and we'll show some helpful shots along the way. I haven't seen my report, but before we dive into it, what is Neo7? Right.

So this is the next level of really personalized peptide therapy.

Okay.

Where, as you mentioned, we collected your blood and your urine and that gets sent to a specialty lab.

Okay.

And they have this fancy platform combining AI technology with human intelligence. And the platform stands for Precision-Based Immuno-Molecular Augmentation.

Okay.

It's a handful. It's a mouthful. And they actually do long-read exome. Of your whole body sequence and the machine—

They do what of the body sequence?

The long reading of the exome.

Okay.

All of your sequences.

You call it the exome?

Exome.

Exome.

Long reading. And I'll show you in the report. And it will kind of prioritize all the faulty pathway. And based on that, which we're going to go over, they design the peptides specifically for you to mitigate those faulty pathways.

Okay. So if I'm understanding properly, if you look at aging, a lot of times you hear about like multiple organ pathways of aging. Usually people name like 12, like the cardiovascular system and the immune system, et cetera, musculoskeletal, nervous system, and gut, so on and so forth. If you look at some research you can find online, for example, people do multi-omic analysis using DNA sequencing to see what kind of things you might genetically be predisposed to. It sounds to me like what this is, is quantification of blood and urine to look at markers for certain organ systems.

It's kind of look at the epigenetic level.

Okay. What's epigenetic? What are the genes actually manifesting? Right.

Also, as you mentioned, we know like the 12 to 16 hallmarks of aging.

Okay.

This test is actually look at all the hallmarks of aging.

Okay. Page 2 here. So page 2 shows these hallmarks of aging as you can see on the screen. Telomeres, inflammation, mitochondrial DNA, oncogenic potential or carcinogenic potential, cellular senescence, cells aging, autophagy, cell cleanup, metabolism regulation, microbiome health. Sleep and stress regulation. Those are the 10 parameters that they're looking at with this test.

Okay, exactly. And so this is kind of a graph to look at.

It's page 3. I almost, almost should have brought my spectacles, but I've still got, still got the vision. I can see it. It'll be bigger on this, it'll be bigger on the screen for people. Okay, so they call this a histogram. So I've got the same 10 hallmarks of aging that you just showed me on page 2, and then there's like this bar next to each. What are these bars showing?

So, the reds are the one that we want to fix. And the higher the bars, the more abnormal signal.

Okay, red is not great.

Right. And so, for you, as you can see, you're a healthy guy, but still telomere maintenance is one of the bigger red bars.

Okay, so the end caps of DNA, this might indicate that they might be shortening to rapid of a rate, right? Okay.

And that correlates with longevity, right?

Yeah.

And, uh, another red, uh, hallmark information— it's not bad, but it's okay there. Uh, your mitochondrial stress and mitophagy is also something to—

mitophagy being the natural mitochondrial, like, cleanup process, like old ones dying, new ones being generated. DNA repair is probably the one that looks the most affected in a, in a deleterious way, right? Okay, correct. Interesting.

But then you do have some greens, which is good. Okay, so this means that, you know, oncogenic potential, the potential for cancer, it's not—

cancer risk low, cellular senescence or cellular death besides the mitochondrial piece, low, autophagy, natural cellular cleanup, maybe need some help, metabolism and endocrine, that's your hormone system regulation, sleep and stress regulation. Look, I knocked it out of the ballpark on that one, right? Yay. And GI and microbiome, Biome Health. Yeah, that one's looking good too, right?

And we did the GI map and we did the GI protocol.

Yeah.

And actually it's—

yeah, yeah, yeah, exactly. We did kind of like a leaky gut protocol.

Yeah. So this is kind of like going over your— all the hallmarks and talk about your specific—

okay, so page 4 just goes into— scroll back up there for just a second. Yeah. So page 4 is explaining what— so it shows which scores are unfavorable and what that means. Okay. So that's useful.

All right.

I'm not going to read that to everybody on the video, but okay. It's just a deeper dive into what it means for those pathways to be unfavorable or favorable. And what was the title of this page? The protein patient-specific key targets. Okay.

So this one, anything that's red and is elevated, that's like the upregulation of unfavorable targets. So for you, you have TNF, you have this galactin-3 that the role is to have the design peptides to mitigate these.

Right, right. Galactin-3 would be inflammatory related. So, so a TNF to a certain extent.

Right. Fibrosis, inflammation.

Lamin A/C is what they measured for DNA damage. I know this is super nerded out for everybody watching, but these are the specific markers or targets that they identified that they could target. Are they identifying these as pathways or targets that one could, uh, for lack of a better scientific term, like aim a peptide at?

Right.

Okay, got it. So lysosomal protease that disrupts autophagy. Okay. Uh, leptin signaling. Okay. And superoxide dismutase, key antioxidant enzyme. So those are the specific targets that we're aiming peptides at.

Okay, and so on this side, these are all the protective targets, but they're downregulated. So now we want to upregulate them.

Okay.

These are the things that should not be upregulated. They're unfavorable. Okay.

Yeah. So we want to make the down arrows go up, the up arrows go down.

Exactly.

Okay.

Exactly. So these are just more in-depth research, in-depth explanations.

Cool.

Okay. And then part of the design of the peptide, they also add SF31. I'm sure you've heard of that. That's the naked peptide. Particularly to also to optimize mitochondrial function. And so you're going to have a combination of—

Are they able to synthesize SS31?

Yeah.

I thought that was one that was like now in the realm of the pharmaceutical industry. Oh, they can make it?

Right. Interesting. So that is combined. So this is the naked peptide, off-the-shelf peptide, but it's it's also combined in with your peptide from Neo7.

What do you call a naked off-the-shelf peptide?

So these are the peptides that we all know.

So, and they modify them?

Yeah. And we use the same peptide for everyone.

Okay.

But these, the rest of that would be just NF-1 just made for you.

Okay.

Yeah.

Okay.

So basically, so go back down to that. Okay.

I want to see. So these are the actual peptides, precision peptide description. So these next few pages would be the actual peptides they've identified that they're going to synthesize, right?

And, and it's not going to mean they being Neo7, right?

Okay. Right. All right. So when they make these peptides, um, are these— what else is farther down? Is it just research at that point?

Yeah. So these are like kind of like, yeah, what they're trying to target.

Okay. So they have a lab where they're synthesizing these peptides Or what are they doing?

So they have a specialty lab to analyze your blood work and to make the design. And then once they have the design, they ship that to a specialty compounding pharmacy.

Oh, okay. So they're working with a compounder. Okay, interesting. And then the compounding pharmacy, are they using off-the-shelf peptides or are they—

No, they're going to use this formula.

Okay. What would be— so SS31 is one of the products.

So that is part of that, but it's going to combine to this.

And did they combine all of that? I'm assuming based on pH balance and stuff, they can't put all the peptides in one bottle.

That, I don't know how they make it.

Okay.

How they make it.

So then they ship them—

To you.

They ship them to me. And then there's an injection schedule that I use to target these specific organ systems.

Correct. So the whole program, you're going to have 120 vials.

120 vials every day?

No.

Thank you.

So you're going to keep them in the freezer.

Okay.

And then you just pull out and do 2 injections a week. Oh, until you are done.

Okay. So this is standard, pull it out, reconstitute it. If it's in the freezer, it's going to be a powder.

Right.

And then inject twice a week. And those are the peptides that are specifically targeted for for these organ systems. Interesting.

Right.

So how many, how many different peptides? So if it's a 120 bottles, for you, these are the target. So there's going to be 1, 2, 3, 4, 5, 6 different peptides. So it says the target but doesn't say the name of the peptide they'll be using for that target.

It would be, it would be these that, uh, that doesn't make—

oh, okay. So those peptide sequence codes, when you see like NB21002-96R01-1, That's— and then it says with NAD, so they add NAD to it, right? Okay, so they've got 5 peptide sequence codes. They'd be putting me on 5 peptides— no, 4 peptide sequence codes. Yeah, and then they combine those with NAD. But I'm assuming 4 peptide sequences are probably targeting those 6 pathways because this one is for 2. Yeah, multiple pathways. They each— yeah, the top 3 target 2 pathways, the last one targets pathway. This is fascinating.

Yeah.

Interesting, right? Wow. And do they— obviously this is something I know people ask— do they then retest blood and urine to see what's happened after a certain amount of time?

That, that was my next, uh, comment. So we have the option of doing that. And as the, the, the page that we show with all the red and green, um, Not all of my patients, not all of them do the repeat test, but the one that did is eye-opening. You can see the—

oh, you've had patients do test, protocol, retest, right?

Um, and you can see like the normal—

how long is the period of time between the test and retest?

So the 120 vials of peptide, it will take around 9 to 12 months.

Yeah, you're waiting until you've gone through all of those. Okay, so possibly up to a year, then you retest.

And then you go through the same process. It takes about 4 to 5 weeks to get the test result.

Okay.

And then another 4 weeks or so to get the peptide. And then go through the—

interesting—

kind of like a year-long program.

Okay.

But as I mentioned, we've seen significant improvement. So that's really fun.

So this is not something where people could like order a test kit from Neo7 to their home and do this. They would need to like call you guys or find a clinic that does something like this.

Correct. So there are clinics including this one and will provide us. So yeah, you apply for the protocol.

Okay.

There's a study.

Do you guys have an application form like on your website or do they just call you?

So there's both on the website and then they can submit and call.

Okay. I'll make sure to put stuff in the video description for how—

Yeah. And for this, we have 3 separate tracks. One is for people with cancer.

Okay.

And then another track is for chronic condition, like autoimmune condition, neurodegenerative condition. And so forth. And then what you did was the resilience because you healthy, but we want to optimize. Okay, so there's different track depending on—

so I'd be on the increasing cellular resilience protocol, but then is that— so if you're on like the resilience pathway, is that, um, still dependent on your blood and urine results, how they then tweak that particular path that you're on? Interesting. Wow, I'm excited.

Yeah.

Okay, so I just follow instructions when these things show up at the house. Correct.

Yeah. So typically we do a titration dose. For you, you go up fast.

Okay.

And then sicker people, we go slower.

Okay.

And as tolerated. Yeah. So it's truly personalized and precision-based.

Interesting.

Based on your genetic and epigenetics.

And yeah, yeah, here's what I want you guys to do. Um, if you find this stuff fascinating, this barely scratches the surface of what I talked about with Dr. Wen on our first podcast and our second show. So right here where you're watching this video, you can click to watch either of those shows. You can see the description where you can reach out to them if you want to learn more about this protocol, and then leave your questions, your comments, and your feedback right there in the comments section. Hit subscribe if you dig this stuff. Cutting edge. And this is what I like to do, is find people who are doing cool things that hopefully make you healthier and live longer, or at least longer, healthier, at least healthier during the years that you are here. Yeah, and prettier. There you go. Thanks for watching, you guys.