Bryan Johnson stopped drinking wine because of its caloric content, about 72 calories per 3-ounce serving, and its effect on sleep. Blueprint doesn't forbid alcohol; the science on moderate drinking versus abstinence is mixed. Johnson follows the data, not a prescription.
Chapters
And then I have a couple bottles of wine. I stopped drinking wine because it was too expensive. From a caloric perspective, 3 ounces, I think was around 72 calories. So when I have friends over, I'll offer them a glass of wine. Some say yes, some say don't. Alcohol in moderation is reasonable. Blueprint is not to tell people what they should or should not do. It's meant to follow the data, the science on alcohol. There's a number of different conclusions people have drawn in terms of no alcohol or Moder moderate alcohol. I don't do alcohol at all, primarily from a caloric perspective, but also because it just wrecks my sleep if it's anywhere close to my bedtime.