Bryan JohnsonFounder of Blueprint and Don't Die

I take 100+ pills EVERY day. Every pill needs to fight for its life

19 Apr 2023 · 1 min

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In this segment, Bryan Johnson walks through his morning supplement routine, which he consumes with a 10‑ounce beverage he calls the “Green giant.” After the pills are taken, about 4–5 ounces of the drink remain. He lists the core compounds he includes—garlic, calcium (CA), alpha‑ketoglutarate (AKG), nicotinamide riboside (NR), coenzyme Q10 (CoQ10), ferritin, vitamin D, blueberry flavanols, and turmeric. Johnson emphasizes that no supplement is added arbitrarily; each must first demonstrate measurable benefit in his own body. He describes a feedback loop where biomarkers are monitored, the organ’s response is evaluated, and only those supplements that meet the predefined efficacy criteria remain in the regimen. The overall message is that his 100‑plus‑pill protocol is entirely evidence‑based, avoiding trends or guesswork.

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So these are the pills I take on waking and I take this with the Green giant. It's about 10 ounces of fluid. I have about 4 to 5 ounces left after taking the pills. But a few things in here like garlic and CA, AKG, alpha ketoglutarate. I take NR, CoQ10, ferritin, vitamin D, blueberry chocolate flavanols, turmeric. So we take these pills and nothing in here is super superfluous or nothing's like, oh, that'd be nice to add because we think that's a cool name or an interesting thing. Every single supplement has had to fight for its life to be included. And every supplement we take we measure inside my body. So we see the exact situation of saying the organ speaks, evidence is consultant, I do it and then measurement again. And we say, is this supplement doing what we intended it to do? Nothing here is just guesswork or human opinion or because it's trendy, it's entirely based upon what my body's reporting out with data.