Bryan JohnsonFounder of Blueprint and Don't Die

I've slowed pace of aging by equivalent 31 years. How? 1. Evidence 2. Protocol 3. Measurement

30 Jun 2023 · 0 min

Watch on YouTube

0:21

In this segment of his YouTube video, Bryan Johnson outlines the systematic schedule he uses to monitor biomarkers related to aging. He measures core body temperature, weight, body fat, and muscle mass every day, tracks DNA methylation (a marker of biological age) once a month, performs whole‑body ultrasound scans quarterly, and undergoes a full‑body MRI once a year. Johnson emphasizes that each metric has its own optimal frequency and that as more longitudinal data are collected, the measurement intervals are continuously refined to improve the precision of his anti‑aging protocol.

How often are you doing these measurements? Each one is different. Like for example, I measure my core body temperature daily and then weight, body fat, muscle mass daily. Whole body MRI is annually. We typically do whole body ultrasound every quarter. DNA methylation is monthly on speed of aging. So everything has its own frequency and we're fine in each one. As we get more data, the frequencies are refined.