Bryan Johnson plans to cure his autoimmune gastritis by sequencing a million immune cells to identify which ones attack his stomach, then testing targeted drugs on a frozen bank of his own cells before using them. Single-cell sequencing, stomach biopsies, and bi-weekly blood draws will map the exact immune cells causing damage so therapies can eliminate only those "criminal" clones while sparing healthy ones.
My stomach is eating itself. Here's my plan on how we're going to cure it. We decode 1 million immune cells. Immune cells are civilians. Each one has a key that stops a threat. Some of my civilians are criminals. Their key attacks my stomach. A standard blood draw shows civilians but not keys. The blood test I did shows both. We see the keys and identify our suspects. From there, we take a live sample from my stomach, the crime scene. The blood test shows the attack is happening, not who's doing it. We grab the live cells, match it to the blood test, and catch the criminal in the act. While we work to find a cure, we monitor the crime scene. Blood tests every 2 weeks paired with wearable data. These are our cameras. We need a decoy, so we make a copy of my immune system, take a huge sample of my cells, and freeze them. Now we have Bryan in a dish. We test new therapies on the decoy first, never on me until it's safe. These frozen cells are also a backup for targeted rejuvenation therapies in the future. Then We build the therapy just for the criminals, one that shuts them off and leaves the civilians unharmed. We test it twice, first on Bryan in a dish, then in a computer model of my body. If both pass, we'd launch the attack and make the arrest. Case closed.
