Bryan JohnsonFounder of Blueprint and Don't Die

part 1: i traveled to London to talk about don't die

15 Oct 2025 · 1 min

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In a live panel at London Tech Week, Bryan Johnson and several speakers discuss the accelerating pace of artificial intelligence and its implications for human longevity and evolution. Johnson emphasizes his personal conviction that he does not want to die, framing this desire as a rallying call for humanity to pursue technologies that could prevent death. Speakers echo the concept of "longevity escape velocity," suggesting that a single breakthrough could enable indefinite lifespans. They argue that AI-driven drug design could cure most diseases within a decade and enable highly personalized medicines tailored to individual metabolism, dramatically reducing side effects. Johnson also highlights the difficulty of predicting AI's future trajectory, noting that the rapid pace makes foresight challenging, yet he views this moment as a pivotal, transformative point for humanity. The conversation blends optimism about AI's potential to improve human health with a philosophical inquiry into what it means to evolve as a species in the age of intelligent machines.

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You're gonna die of old age, which is fine. That's not good. You want to die, you don't have to. Just a disease. We can cure it.
So maybe Brian Johnson's right when he says, don't die.
Don'T die ever.
But, you know, he's saying, like, don't die before we get to the technology.
Right? Longevity, escape velocity. You want to live long enough to live forever? It's one breakthrough away.
It's London Tech Week. We're live with guests from over 130.
Around the world. We all intuitively know that AI is happening fast. So our ability to predict the future is becoming very, very, very hard. We just can't see anymore. The one thing I do know is I don't want to die. I think the world is beginning to digest AI, and this is a big moment, bigger than we can imagine.
I think we could cure most diseases within the next decade if AI drug design works. And then there could be personalized medicines where it minimizes the side effects on the individual because it's mapped to the person's individual illness and metabolism and so on.
We talk about the progress of our smartphones and AI models, but we don't talk a lot about human improvement. There's this open question of, like, what does it mean to evolve as a human? And not only how is AI positive, but how it makes us humans better.