Bryan Johnson spent $300 million from selling Braintree to fund Blueprint, his anti-aging program aiming for "aging escape velocity" where rejuvenation outpaces aging. He takes metformin off-label and follows roughly 100 interventions across diet, exercise, and organ-specific strategies, publicly sharing every measurement and mistake.
Chapters
This one is Metformin. This is given typically to diabetics. It's been also taken off label for longevity purposes. The people who I admired the most did things typically over a multi decade time frame. People who, in their time and place, they surveyed the landscape of things that they can do and they identified the thing that can barely be seen and say, I'm going to try to do that thing. Yep, good. Here comes the scary pictures. I started Braintree when I was 27 years old. I bootstrapped the company for the first four years and we were profitable every month. And then I raised money and we sold it for 800 million. And then I made 300 million of that at the age of 34. I thought it's time to try to do something meaningful on that kind of multi decade timescale. My objective with blueprint is to demonstrate aging escape velocity using the best science, trying to do all the appropriate interventions to neutralize my aging process. 1.8. So even better than last time. So I think my first one was 3.4. A few things have distinguished what I've done to date. As far as I know, I'm the only person that has publicly posted my data. So I'm not saying here's my protocol and believe me, I'm saying here's my protocol, here's all my data, and here's what I'm experimenting with next. And here's where I've made mistakes and here's where I'm trying to fix it. It's really a stacked process of maybe 100 different things I do. Because you have to think about the body in its entirety. 11 8. Is that right? Mm. How the heart ages is different than how the lungs age. And how the lungs age is different than how the brain ages. You have to really think about it from a holistic perspective. So it's the common things like diet and exercise, but it's also a much broader consideration. So I have a team of doctors that I work with and we just go through this rigorous process of measurement, gold standard science implementation. Measurement is produced near perfect health for me, no matter how extreme I've had to be, no matter how eccentric people perceive me to be, because I'm outside the norms. Demonstrating that age can be arrested would change everything.