Omeprazole Side Effects and Mechanism of Action | Nursing Pharmacology

17 Jun 2021 · 1 min
0:44

The video provides a concise nursing‑focused overview of omeprazole (Prilosec). It begins with a brief introduction and a call to download a free pharmacology cheat sheet. The core content covers: the generic and trade names, pharmacologic class (proton‑pump inhibitor) and therapeutic class (gastric acid suppressant), primary indications (GERD, gastric ulcers, heartburn), and the mechanism of action—blocking the H+/K+ ATPase proton pumps in gastric parietal cells, thereby reducing gastric acidity while leaving overall gastric volume unchanged. The presenter then lists common adverse effects (GI upset, constipation, increased risk of C. diff), outlines nursing assessments (abdominal exam, bowel sounds, stool color, signs of GI bleed or C. diff), and notes major contraindications/precautions (impaired liver function). Patient education points include taking omeprazole on an empty stomach 30 minutes before breakfast, avoiding NSAIDs, aspirin, and alcohol, and completing the full prescribed course. A nursing consideration emphasizes that therapeutic effect may take 3–4 days to manifest, so patients should be encouraged to continue therapy. The video concludes with promotional messages for a medication database within the Nursing SOS membership, a reminder to like/subscribe, and a motivational sign‑off.

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