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In this brief presentation, Dr. David Perlmutter addresses adults in their 70s and 80s who wonder whether it is too late to take steps to protect their brain health. He emphatically states that it is not too late, citing two major multidomain lifestyle intervention trials—the 2014 FINGER trial and the more recent POINTER study published in the Journal of the American Medical Association. Both trials involved participants at risk for cognitive decline (e.g., metabolic issues) but without a diagnosis of mild cognitive impairment or Alzheimer’s disease. The studies demonstrated that engaging in a combination of lifestyle changes—regular physical exercise, dietary modifications, stress reduction, and targeted brain‑training activities—led to measurable improvements in cognitive function. Dr. Perlmutter concludes with a motivational call to action, urging seniors to adopt these practices now, assuring them they will be glad they did.

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