You Might Have Had Lyme for Years Without Realizing

28 Feb 2026 · 5 min
4:32

In this video, Dr. Diane Mueller addresses a listener’s question about whether Lyme disease can persist unnoticed for years and later flare up. She explains that Lyme disease is caused by the bacterium Borrelia, which can enter dormancy, hide in hyaluronic‑acid‑rich tissues such as joints and eyes, and reactivate when the immune system is dysregulated by stress, toxins, or illness. Mueller notes that transmission is not limited to ticks; some mosquitoes can also carry the bacteria. The classic bullseye rash appears in fewer than one‑third of cases and may be hidden on the scalp or hair, leading to missed diagnoses. Because dormant Borrelia can reactivate in various tissues, chronic Lyme can mimic fibromyalgia, chronic fatigue, migraines, movement disorders, and other conditions, making it hard for clinicians to recognize. She highlights that many doctors lack Lyme literacy, resulting in inadequate testing—often using inaccurate assays that yield false‑negative results. Mueller promises a forthcoming video on proper Lyme testing and directs viewers to a free quiz at getwellquiz.com for guidance on appropriate lab tests. The overall message emphasizes the need for awareness of chronic Lyme’s hidden nature, its potential triggers, and the importance of better diagnostics.

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