Dino Prato uses donor immune cells as a temporary strike team against blood cancers. T cells and NK cells are isolated, activated with cytokines, then infused to attack cancer cells before disappearing, avoiding the long-term complications of traditional stem cell transplants.
Stick with me as we attack blood cancers. In transplant medicine, there's a real effect called graft versus host. That means the donor's immune cells can recognize the blood cancer and hunt it down. That's powerful, but here's the price many patients pay. An allogeneic stem cell transplant— their immune donor cells can land them into the hospital, and the complications can be serious with graft versus host. What if we could borrow the cancer-killing power but not keep the donor cells long enough in the body to cause any known as graft-versus-host problems. In our international facility, we've adopted this technology to help with blood cancers. And from the donor blood, the immune killer cells are collected, and these include T cells, natural killer cells, and we power them up with like cytokines that gives us signaling. And then we get them energized, focused, and we re-return them to the patient, and they go in like a strike team. Those activated donor cells are infused into the patient, and now they can hunt down and kill these cancer cells that have gone rogue.
