Dr. Dino PratoEnvita Medical Centers · Founder and CEO at Envita Medical Centers

N of 1 — The Future of Cancer Care

1 Nov 2025 · 0 min

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In this brief excerpt, the speaker introduces the concept of N‑of‑1 precision oncology, describing it as a hyper‑personalized cancer treatment built on more than a thousand data points—including DNA, RNA, spatial biology, and immune profiling—to create a custom therapeutic plan for each patient. The speaker contrasts the success of early‑detection, conventional oncology with the dismal 2% palliative response rate seen in late‑stage disease, arguing that traditional approaches are insufficient in the era of AI and big data. The message is a call to move beyond conventional methods by leveraging AI‑driven integration of multi‑omic and spatial data to deliver truly individualized cancer care.

N of one where treatment is built on you. It's a custom treatment plan that uses a thousand plus data points that involves everything from DNA, rna, spatial biology, immunity to custom build a treatment for you. It's become so important to know the difference. Early detection is important and that's where we've seen conventional oncology really do its best. But in late stage cancer, with this 2% palliative response rate, it is not enough. It is not where we belong, especially in the time of AI and data. We need to go way beyond that and that's what precision does.