Dino Prato, NMD discusses insulin as a peptide hormone that can potentiate chemotherapy. He describes insulin potentiation therapy, a microdosed approach guided by biomarkers and blood-sugar monitoring, designed to trigger immunogenic cell death and improve cancer treatment outcomes.
What if a simple peptide hormone could help your treatment hit harder with less drugs? The peptide hiding in plain sight is insulin. In the early 2000s, we worked for many years using a treatment called insulin potentiation therapy. Delivering chemo dosed with insulin to make the low dose chemotherapy more effective. As our precision oncology improved over the years, we realized it only made sense when specific biomarkers were present. That's when we watched blood sugar closely and only used it selectively. We developed this metronomic microdosed approach with the focus of releasing dams damage associated molecular patterns, stimulating the immune system. Micro dose fractionated treatments with the right primers to push tumors towards an immunogenic cell death. Not just managing the cancer, but getting rid of it.
