Histamine, Mold & Menopause: Why Your Symptoms Suddenly Change

14 Oct 2026 · 47 min
Menopause Mastery

14 Oct 2026 · 47 min

0:00

In this Menopause Mastery podcast episode, Dr. Betty Murray interviews functional nutrition practitioner Marika Sterng, creator of the SENSE framework, about the sudden emergence of histamine‑related symptoms during perimenopause and menopause. Marika shares her personal journey from digestive upset to skin eruptions, sinus issues, and systemic reactions after a hidden roof leak introduced black mold into her home. The conversation explores how fluctuating estrogen and declining progesterone remove natural buffers on mast cells, amplifying histamine release, and how histamine in turn can stimulate estrogen production, creating a feedback loop. They discuss the role of environmental toxins—especially mold and mycotoxins—and the difficulty of detecting and remediating them. Genetic variations that impair histamine clearance (DAO, HNMT) and detoxification pathways (GSTM, GSTT1, COMT) are examined as reasons why some women experience severe reactions while others do not. Practical diagnostic recommendations include comprehensive blood work, organic acid testing, gut panels, DUTCH hormone testing, and targeted genetic panels. Management strategies cover low‑histamine diet, mast‑cell stabilizers (quercetin, luteolin, vitamin C), gentle detox supports (castor oil packs, infrared sauna, Epsom‑salt foot soaks), lymphatic drainage, and careful hormone replacement (progesterone, estradiol) tailored to individual genetics. The hosts introduce a “histamine bucket” model that integrates hormones, mold exposure, genetics, nervous‑system stressors, and dental/airway factors. Finally, Marika offers a free 7‑day Calm Energy Reset guide to help listeners begin systematic self‑investigation and symptom reduction.

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