Jeffrey Bland identifies five mechanisms driving aging: chronic inflammation, mitochondrial dysfunction, immune remodeling, epigenetic drift, and cellular senescence. Each is modifiable through information delivered to the immune system, offering a way to slow aging and prevent frailty.
An immune system that's compromised, it's less resilient, that is biologically aged, is an immune system that translates into frailty. Frailty on many, many levels. So how can you then do something about your immune system? Well, we're starting to see geroscience, the science of aging, start to tell us that there are key mechanisms of aging. Chronic inflammation, mitochondrial bioenergetic dysfunction, where the energy process centers of our cells are gaining energy from food and converting it into motive and cerebral energy. Our immune remodeling, our epigenetic drift, and cellular senescence are all tied to our biological aging process. The good news is they're all modifiable. They're modifiable by sending the right information to our immune system.
