Boosting Wellness: The Power of Nitric Oxide for Body and Microbiome

Hi, everybody. I'm Dr. Sandhya Moldovan, periodontist and nutritionist. Welcome to the Holistic Dentistry Podcast, the show that gives you the tips and tools to detoxify your mouth for a healthier body as we explore together the root cause of disease. Remember, you're not healthy until your mouth is healthy, so take care of it.

In the most natural way. Welcome to today's show, everyone. I'm super excited to have Dr. Brian here talking about nitric oxide, a topic that probably a lot of you don't know much about. A lot of dentists don't know much about this. We really don't talk about it in dental school. Even when I was a periodontist, which is an inflammatory condition, talking about periodontal disease, we didn't talk about nitric oxide production. So, Dr. Brian, welcome to the show.

This is. Thank you so much for having me. It's great to be with you.

Same here. So you have quite an impressive resume, I have to say. You've, like, gone through University of Texas, you've studied with some really famous scientists, and you're talking right now, globally about, you know, the issue of nitric oxide. And how did you end up studying nitric oxide to begin with?

Well, as you can probably appreciate, every career is a journey, right? And so, you know, I got interested in nitric oxide in the late 90s, early 2000s. I was a student at LSU School of Medicine working on a PhD in molecular and cellular physiology. And a Nobel Prize had just been awarded for the discovery of this gas called nitric oxide. It was realized that the body produces this substance. Once it's produced, it's gone in less than a second. But it controls a number of important biological functions from regulation of blood flow and circulation, Oxygen delivery mediate an inflammation. And so we knew it was extremely important. But there were still a lot of unanswered questions, like, how does the body make nitric oxide? What goes wrong in people that can't make it? And then, you know, there were certainly no ways to restore or recapitulate nitric oxide production or signaling. So for me, it was a ripe area. We knew it was important. A lot of unanswered questions. So that really set the stage for my career to go out and really devise some important experiments and get some answers to some really important questions. And now, fast forward 25 years later. We know how the human body makes nitric oxide. We know what goes wrong in people that can't make it. And now we have technology to completely restore nitric Oxide production.

So we're talking about nitric oxide, not nitrous oxide, which is common in dentistry, by the way. Right. So there's a big difference between the two. Our body does not produce nitrous oxide, just nitric oxide.

Yeah, common misconception because I hear people talk about nitrous oxide. Oh, how they love nitric oxide. Well, it's. Yeah, it sounds similar, but it's completely different molecules. So nitric oxide, what we're talking about is no. 1 nitrogen, 1 oxygen, nitrous oxide, dental anesthetic, or what you referred to as laughing Gas is N2O. So completely different molecules, completely different biological functions.

And we definitely should be loving nitric oxide more than nitrous oxide, considering what it does for our body.

Yeah, no, it's foundational. You know, one of the beautiful things about what we're learning is how we can integrate this molecule into dental medicine. You know, and you as a, in periodontics, you know, certainly understand the oral systemic link and how oral pathogens contribute to cardiovascular disease. So the question today in dental medicine is how do you selectively eradicate the, the pathogens that cause periodontal disease, caries, gum disease, gingivitis, while maintaining a healthy ecology of the non pathogenic commensal microbiome? So that's really the trick going forward, not just in dental medicine, but in medicine in general.

Yeah, absolutely. Like microbes are so important in human health, we can't live without them. But how microbes really involved in the production of nitric oxide?

Well, obviously the microbiome in the gut is completely different that in the mouth and the colon and all parts of our body on the skin. So these bacteria that live in and on our body are designed to do things that we as humans can't do. It's a true symbiotic relationship, meaning they do things and provide important metabolites that humans need for normal metabolism and for optimal health. So what we've learned over the past 20 years, that they're bacteria that live on the crypts of the tongue that are part of the oral microbiome. And what they do is convert nitrate that we get from our diet into bioactive molecules from nitrite to nitric oxide. And what we're finding is that these oral bacteria are responsible for the regulation of systemic blood pressure. So this is a completely new paradigm in, in cardiology and vascular biology and on the maintenance of, of healthy blood pressure. So we disrupt the microbiome to our own demise. And I think that's where we're learning that, you know, chronic use of antiseptic mouthwash, fluoride, which is an antiseptic use of antacids, all shut down nitric oxide production and it's leading to systemic disease.

That's pretty amazing because there's so many products out there on the market, so many mouthwashes that contain fluoride, probably 99% of them at this point. And, you know, as a biological dentist and periodontist, we don't recommend they use a fluoride. And now you gave us another reason why we shouldn't be using fluoride or any kind of antimicrobial solutions, you know, that could contribute to destroying your own microbiome. What about like tongue scraping, for example, Is that bad or is it because. Has any been studies done on that?

Yeah, interestingly, we published a paper in 2019 on tongue scraping. And so it's really some interesting data. And it took us a while to interpret the data. But here's what we find, that if you do tongue scraping, the people that tongue scrape seem to have better blood pressure. But here's the kicker. Tongue scrape and use mouthwash that causes a severe increase in blood pressure. So I think tongue scraping itself is good. But if you tongue scrape and then use fluoride or an antiseptic, it seems to have really an adverse effect on causing an increase in blood pressure. In fact, in one patient, we made his blood pressure go up 26 millimeters of mercury simply by tongue mouthwash. So very drastic effects. And I think what. What we're learning here is that the microbes, so tongue scraping itself is kind of like tilling the soil. You improve the diversity of the microbiome. But when you do that and you open up the crypts of the tongue and you use an antiseptic, you get really effective killing of the oral microbiome that shuts down nitric oxide production, causes blood pressure to go up. You lose the protective benefits of exercise. And so all these things that are killing bacteria in the mouth, in and on the body are really having some adverse health effects that we're just now understanding.

Yeah, very interesting. Yeah, for sure. So what are some natural ways to boost nitric oxide production in the body?

Well, that's probably the most common question I get. And I tell people that the science of nitric oxide is really complex and complicated, but the solutions are really pretty simple. So you only got to do two things. Stop doing the things that disrupt it and start doing the things that promote it. So if we take those one by one, what does that mean? Well, if you're using mouthwash, you have to stop. If you're using fluoride in your toothpaste or fluoride rinses, you have to stop. You know, we're finding now, and data for the past probably 10 years has revealed that antacids, specifically proton pup inhibitors, completely shut down nitric oxide production. In fact, people who have been on PPIs for three to five years have a 40% higher incidence of heart attack, stroke and Alzheimer's. So if you have to get off antacids, your body cannot and will not heal without stomach acid. So if you eliminate fluoride, antiseptic mouthwash and antacids now, your body can actually produce nitric oxide and you can actually enhance that through throw in some more green leafy vegetables, as little as 20 or 30 minutes of aerobic exercise a day, and then 20, 30 minutes of sunlight exposure, which will stimulate mitochondrial activity and release nitric oxide bound to metals. Those things right there are quite simple. Then when all else fails, Americans are programmed to want to take a pill or something, a magic bullet. Then we have product technology that actually produces nitric oxide for you. So if your body can make nitric oxide, our products do it for you and we fix the reason your body can't make it. And that's the difference between what we do and all the other so called nitric oxide companies out there.

So how does someone's body stop making nitric oxide? What happens exactly?

Well, you know, what we're finding is the American lifestyle, seems like everything we do in the Western world shuts down nitric oxide production. So we take those kind of pathway to pathway. So there's two pathways through which the human body makes nitric oxide. One is through an enzyme found in the lining of the blood vessels called our endothelium. And the older we get, the less functional that enzyme becomes. And really it's due to the inflammation, oxidative stress and immune dysfunction that occurs due to the western diet or physical inactivity or smoking, or all the standard cardiovascular risk factors or inflammation. And infections in the mouth can uncouple the NOS enzyme. So those are all the standard risk factors that lead to endothelial dysfunction, loss of nitric oxide production. Then now we're understanding the role of the oral microbiome. Things like mouthwash, oral infections, whether they're asymptomatic infections from root canals or symptomatic infections, gum disease, gingivitis, all of those disrupt the oral microbiome, shut down nitric oxide production. And then by definition, the patient becomes nitric oxide deficient and then starts to develop the symptoms of nitric oxide deficiency, which are.

So what are some of the symptoms, by the way? For nitric oxide deficiency?

We're finding there's a hierarchy of symptoms. So the first sign and symptom of nitric oxide deficiencies is erectile dysfunction, and that's in both men and women. So if you can't dilate the blood vessels of the sex organs, it's a sign of vascular dysfunction, nitric oxide deficiency, and you get erectile dysfunction. Second, you start to see an increase in your blood pressure. Two out of three Americans have an unsafe elevation in blood pressure. Three, you start to get insulin resistance and diabetes because nitric oxide is required for insulin signaling and glucose uptake. You develop exercise intolerance, you get winded and short of breath. When you begin to exercise, you start to lose your memory, develop mild cognitive disorders, vascular dementia, Alzheimer's. So that's just the short list. But it's really the major symptoms and syndromes that plague the world today can all be explained, at least fundamentally, by a lack of nitric oxide production.

So we really have an epidemic of nitric oxide deficiency in the world, considering that, you know, the conditions you mentioned are rampant.

No, absolutely. I think every single age related chronic disease that we deal with today, they all have. There's four hallmarks of chronic disease. There's low blood flow to the organ, there's inflammation, immune dysfunction, oxidative stress. Nitric oxide controls and corrects all four of those. It dilates the blood vessels now gets adequate circulation and perfusion to the organ. It reduces inflammation, it inhibits oxidative stress, and it prevents the immune dysfunction that you see in chronic disease. When we look at, kind of, and you as a dentist can appreciate this, but the numbers tell us that two out of three Americans wake up every morning and use mouthwash. And there's two out of Americans have an unsafe elevation in blood pressure. And this is not a coincidence. Now we published in 2019 that this is causal. So now we're finding that, and thankful to biological dentists like you who understand this oral microbiome that if we can stop getting people using mouthwash, get rid of fluoride, allow this microbiome to flourish, to repopulate, to improve its diversity, we can restore nitric oxide production. And now you can start getting patients off of antihypertensive medications, which is a completely new conversation in Western medicine, because there's never been a conversation of how do we get Patients off medicines. It's, how do we come back? And we're going to put you on more medications. And we've learned certainly not the answer. And that hasn't made anybody any better.

Yeah, exactly. Now, how do we test for nitric oxide deficiency? I know I was recently at a conference, and they have the strips that, you know, you put some saliva on it and you check, are those accurate? Are there better ways to check for nitric oxide deficiency?

You know, I was the one who developed those test strips about 12 years ago. So that was the first and only really, point of care, noninvasive diagnostic for nitric oxide. So I think they have their. Their place and their utility. But I've gotten away from them because, especially in the dental community, because you can have false positives from an active oral infection. So there are no false negatives. So I like to tell people, if you test your saliva and you're low or depleted, then it tells us that your body's not making nitric oxide, but it doesn't tell us why. But what we find is you can have a patient with all the symptoms and clinical presentations of nitric oxide deficiency, and they light up that test strip bright pink. Well, that doesn't tell us that that person's making sufficient nitric oxide. Upon further interrogation, we found that. That they had an active dental infection. They had active, you know, gingivitis, inflammation in the gums, and that led to a local immune response leading to a false positive in that test strip. So as long as you understand kind of what we're measuring with those test strips, which is salivary nitrite, then I think they have some utility. But I tell people it's not the only tool you should be using. We rely on functional measurements of endothelial function, and we rely on clinical symptoms and clinical presentations.

So typically, when somebody starts to take. I do want to get into the products that are good for us to increase nitric oxide production. How quickly does someone bounce back, so to speak, or they feel better?

You know, everybody's different. So, for instance, you know, I'm relatively healthy. I just turned 50 a couple of weeks ago. But I don't have any symptoms. So when I take our products, I don't necessarily feel any different. But here's what we do know, and here's what we've demonstrated. That once you put that lozenge in your mouth and it starts generating nitric oxide gas, if I put an ultrasound probe on my carotid artery, within about 12 to 15 seconds, I can see Those blood vessels dilate. So I may not feel it, but we can see it and visualize it in real time. Some people feel it immediately when they put the lozenge in their mouth. People who take our fermented bee powder for performance can improve their exercise performance and really have less perceived exertion when they exercise, and they can improve their performance. So everybody's different. But here's what we do that no one else does. We produce nitric oxide the same amount, the same dose over the same period of time, every single time somebody takes the salage.

I love it. I love the scientific approach, the fact that you're measuring that your products actually have an effect on the human body. Because one of the biggest problems with the natural supplement industry is that we don't really have, you know, a standard out there. So a lot of products that claim a lot of things, a lot of products that say, hey, this is great for inditric oxide production, but probably they don't do anything.

You know, we've done this, and, you know, we set the standards in the field. You know, I think you and I just came back from the same conference, and there were a lot of companies out there that petitioned the organizers to not allow me to bring my instruments into the exhibit hall. Because we test products and we call these companies out that are selling nitric oxide products that aren't nitric oxide products. And that's the greatest source of my frustration as a scientist who spent 25 years in the lab trying to understand this, is companies out there basically selling you a bill of goods. Because everybody can say the same thing, right? Based on the Dietary Supplements, Health and Education act of 94, all these supplement companies can say they produce nitric oxide, but they don't. We have instruments and technology and analytics that tell them they can't make nitric oxide. So what we do is very disruptive. And other companies don't like that because we actually call them out through objective measures of nitric oxide production. We test our products that they generate nitric oxide. We test the effects in the patients. And no other company wants to do this because they know their product will not work, will not move the needle, and patients won't get better. But the issue, you know, these companies could kill an entire industry. Because I hear this all the time when people go, nathan, I hear you talk about nitric oxide, but I don't think nitric oxide works for me, because I was taking this product and it. It didn't do anything for me. And I go, no, here's where you were, you were defrauded because nitric oxide always works. You were taking a product that was marketed as nitric oxide but doesn't deliver nitric oxide either because they don't understand the science, they're naive, or number two, worse yet, there's companies out there and it completely go continue to deceive and defraud their customers. And to me that's unacceptable and I'll continue to call these companies out.

Yeah, I agree 100%. Now let's talk about your products that do work. Did you start looking into like products and tell me a little bit about your research into, into that?

Well, you know, it goes back almost 20 years. We discovered and published a paper in 2007 that nitric oxide is a hormone. And so once we figured out that we could make nitric oxide gas, then we started developing these different product technologies. My objective was to develop nitric oxide drugs to put this technology through the FDA to get safe and effective drugs on the market and go through the rigor of FDA clinical trials. But early on we realized that, well, we could use natural product chemistry and basically just recapitulate nature and come to market with dietary supplements that would produce nitric oxide. So that's where we started. So we started developing a lozenge that produces nitric oxide. And then, you know, it became personal for me because my dad, who's a paraplegic from a car accident in 1984, developed a lot of these decubitus ulcers, these pressure wounds that wouldn't heal. And so I started developing a topical nitric oxide for his wounds. And you know, we had a three year old non healing wound that every wound care center that I took him to said we couldn't heal this wound and the nitric oxide healed the wound within, you know, nine months.

So then I thought, okay, lozenge.

No, we did the lozenge for my dad for systemic, but we, I created a topical nitric oxide where we treated directly on the wound. So then now taking these technologies through the fda, we're in phase three clinical studies. But you know, we also brought to market a topical nitric oxide for skin care and beauty. And that's the nitric oxide activating serum that we brought to market in 2019. So we have a, you know, a line of products for skin care, for beauty, for exercise performance. The lozenge is your daily nitric oxide support. But every product we bring to market generates nitric oxide. If it doesn't, then we don't bring it to Market. And that's our brand promise. And that's what we do that no other company does.

That's incredible. I would love to chat with you about the wound healing because, you know, as a periodontist, I do surgery and I have patients that just don't heal well. And it never even crossed my mind to use nitric oxide as a wound healing agent because I thought, oh, vasodilation, maybe I'm going to get more bleeding. So how exactly can we use, or is it wise for me even, let's say, for dental surgery to check patients ahead of time for nitric oxide? Because, you know, I would love to develop in my mind a protocol where I could clinically apply your knowledge to our profession.

Well, you know, we're making headway in the dental community. We've got a number of dental offices and clinics that use our lozenge either before or after any dental procedure. You know, the, the topical. We haven't ascribed that to a dental use yet. So, you know, we're working on that and hopefully have something market next year to apply directly to the gums or on extraction sites or any type of surgical site. But here's what we've learned. That the amount of nitric oxide that we're releasing topically doesn't extend bleed times, isn't affecting platelet aggregation. So that's an important consideration. But what it's doing is most pathogenic bacteria are sensitive to nitric oxide. In fact, nitric oxide binds to the iron sulfur centers of bacteria, shuts down the respiration, the pathogens, the infectious opportunistic pathogens. So we're killing the infection, we're improving blood flow to the site, and then you facilitate healing. And we're actually mobilizing stem cells. And stem cells actually go to the site, repair and replace dysfunctional cells. And basically everything we know about wound healing and tissue regeneration can be explained by nitric oxide.

Wow, that's fascinating. Now, regarding skin care, I have to ask because I always want to have good skin, especially in front of the camera, but how does nitric oxide. I think you're the first skin care line that I've seen having nitric oxide in it. So what does it do for, for the skin?

Well, yeah, you're right. We're the only nitric oxide skin care product on the market, and it's a new category in skin care. As you know, most skin care products are designed to mask or hide the fine lines and wrinkles, the blemishes, the age spots. And we do the exact opposite we get to the root cause. So, you know, when we started developing this, we get. We forget the skin's an organization. Right. Just like the sex organs or just like the heart. And without sufficient blood supply and circulation, that organ fails. And so we thought, well, if we could apply nitric oxide topically and recruit capillaries, dilate blood vessels and start perfusing the skin, then would that have any effect on aging skin? Now we have five published clinical trials and we find that the topical nitric oxide improves blood flow, improves collagen deposition, improves hydration, fine lines and wrinkles go away, very effective at acne, wound healing, scar remediation, rosacea, a number of dermal problems that our topical nitric oxide is really having amazing effects with. But in the skincare and beauty, we can't make those claims. We can say that it improves the tone, texture and clarity of the skin, which obviously it does. But all these other indications, we're taking it through the FDA to get approved indications.

I love it. And I know how much effort. I did my master's at UCLA and I did some research there. I know how much effort research takes to write the papers, to do the research. So I really admire you for that, for putting the effort into your products to have that research to validate what you're saying.

Our job in the basic sciences is to give you clinicians the tools you need to prevent, treat and cure human disease. And so we can only do that once we have a firm understanding of basic mechanisms in biochemistry and physiology. Then once we understand the mechanism of disease, now we can start to develop rational therapies. And so that's where I spent the past 20 years is understanding really the mechanism of nitric oxide deficiency. And once we understood that, then we can develop safe and effective nitric oxide products. And that's what makes me and our companies different than any other company out there. You know, most companies have some talking head or so called expert that's never spent a minute in the lab and would have a hard time spelling, you know, if it wasn't right there before their eyes.

Yeah. So somebody who wants to start taking nitric oxide lozenges or lozenges, is that the best way to take it or is it a powder that's better. You mentioned fermented beets. Like what's the difference?

Yeah. So nitric oxide is a gas. It's naturally produced in the body. So the challenge that's really 30 years is how do you deliver a bioactive gas in a solid dose form. And that's Been my claim to fame. I'm the only person that's ever made a solid dose form of nitric oxide gas. So we did that through the lozenge. And the lozenge is designed to have a resident time of five to six minutes. So you put the lozenge in your mouth, you don't swallow it, you don't chew it, you just move it around. It's activated by your saliva and we release nitric oxide gas. And so it's absorbed beautally. It forms some other intermediate metabolites that can extend the biological half life from 2 milliseconds out to tens of minutes and hours. But we also restore the oral microbiome because of that five minutes that it's in the mouth, on the tongue. We're killing the bad bacteria, we're restoring the good bacteria and we recouple the enzyme that makes nitric oxide in the lining of the blood vessels. So the lozenge is really the, the probably the premier way to produce nitric oxide. But as you know and probably heard that beets have been kind of a hero vegetable for the past 10 or 15 years. But most beets don't have any nitric oxide production. Most beets contain high oxalates and people that are prone to kidney stones have problems. And most people don't like the taste of beets. So we did something a little bit different. We, we fermented our beets, we took out the oxalates, took out the beat pulp, the beat taste the beat color, and we put electrolytes in there and a mitochondrial ATP product. So this powder you put in water and take it as a shot. So as soon as it hits solution, it generates nitric oxide. And that's an amazing product. It's an energy product, a pre workout that has amazing effects on, on performance.

Interesting. Can you overdose on these products? Can you make too much nitric oxide now?

You can, look, you can consume too much water and die from, you know, hypotonic lysis. So dose dictates poison. And that's why we put our bead product in individual sachets because human nature is, oh, if one scoop is good, three is going to be great right now those products out there, because they don't do anything, you can get away with that. But our products are very potent and so we have to control the dosing. But the toxicity of nitric oxide is defined by low blood pressure and a condition called methemoglobinemia. So you'll develop low blood pressure before you develop any critical Stages of methemoglobinemia. But to answer your question, yes, you can overdo it. But when you take our products as indicated or as instructed, you know, there's, there's no problems. We deliver a certain amount of nitric oxide over a certain period of time that completely recapitulates endogenous nitric oxide production.

Okay, and is there like somebody who's an athlete, do they need more nitric oxide or, you know, how do we determine how much we need?

Yeah. Now look, we've got a number of professional and NCAA programs that use my nitric oxide product technology. So as you know, the difference between first and last and well trained athletes, maybe a couple of seconds, right. Or just a 1% improvement in performance. So what we're finding is the nitric oxide can certainly improve performance by every objectable measure of performance, whether it's VO2 Max, whether it's mitochondrial function, anaerobic threshold. Nitric oxide controls and regulates mitochondrial biogenesis, mitochondrial ATP production, the efficiency of oxygen utilization. So every objectable measure of performance can be explained by nitric oxide. So if you can enhance your nitric oxide production through our product technology and improve performance by as little as 1%, you know, that's the difference between a gold medal and last place.

Yeah, that's true. So as we get older, do we need more nitric oxide? Should we increase the dose?

Well, you know, everybody's different and in utopia, in a perfect world, the answer would be no. Because, you know, if we restore the endogenous systems that produce nitric oxide, we wouldn't need to supplement. Right. We give the body what it needs. The body does its job and heals itself. But because we live in a toxic world, the food we eat is depleted of many nutrients and contains a lot of chemicals. We're exposed to emf, environmental toxicants. I think we need nitric oxide. We need daily nitric oxide. Number one, if you're low to replete. Number two, from my perspective, I'm still relatively young. I have ample nitric oxide production, but I take our nitric oxide products every day to prevent that age related decline. So this is a proactive approach. Supplement and restore before you lose the ability to make it.

Absolutely. Wow, this has been such an enlightening conversation. Dr. Brian, thank you so much. Any, any last words or anything you want to add that we haven't talked about?

Well, I, I say all the time that dentists, I think are the most important healthcare practitioners in the world. You know, they can completely solve you of your systemic disease or they can create systemic disease based on what they're doing in your mouth. You know, all disease starts in the mouth. And thanks to people like you who are beginning to understand the oral microbiome and the benefits of preserving the microbiome and not disrupting it, you know, I think we're going to see major strides in dental medicine and how it affects systemic disease. And really, the first line of therapy, when I see people that are chronically ill, that are poorly managed by allopathic medicine, first thing I do is send them to a biological dentist and get their oral infections cleaned up, get their amalgams removed, get any root canals cleaned up, and basically do what you do. And we see remarkable effects of that. But, you know, so I just congratulate you and hope other people in the dental community subscribe to what you're doing, because it really is life changing.

Thank you very much. I mean, my mission is definitely to spread biological dentistry, to make it mainstream, to detoxify the mouth, to keep, you know, in mind the microbiome and what we can do naturally to boost our own immune system, like, you know, using nitric oxide products and really understanding the way, you know, certain molecules and ingredients really are helpful for us to live in optimum health. Yeah. So I love to have a conversation with someone like you who, you know, we understand how, how oral health is so important in overall health. N101.com for anyone interested in finding out more about nitric oxide, you have some interesting things there about nitric oxide production. You also have your own website, drnathensbrian. Where you can watch exactly like the mechanism of nitric oxide, for those of you who are more interested. But I'm super excited to try your products, especially for my patients who are suffering from Sloan healing, my older patients, and really starting to test everyone in the dental office. And I know we have other hygienists and dentists listening to this podcast. I highly encourage you to learn more about nitric oxide production. And we're going to put a link in the show notes for n101.com and you're offering everyone a discount on your products just for trying things?

Sure.

Or listening to this podcast.

Yeah. So I just make it clear to you, it's the letter N, the number one, the letter O number one dot com. And the other thing, you know, I'm not here to sell products. I'm here to provide education. But I'd encourage people to subscribe to my YouTube channel. We do. We'll post this on my YouTube channel. I do lectures, webinars, podcasts, but really encourage people to learn all you can about nitric oxide. Learn the science of it and then, you know, understand the importance of lifestyle strategies and oral hygienic practices. And stop doing the things that disrupt nitric oxide production. Start doing the things that promote it and you'll see a difference in your life and your health.

Yeah, absolutely. Thank you very much and we look forward to hopefully having you again soon.

Do it. Thank you.

Thank you.

Thank you so much for joining me this week. Please make sure you check out the show notes for any links mentioned in the show. If you like today's show, please invite your friends to listen as well. That would mean a lot to me. Do you have a question you'd like me to answer? Message me on Instagram. Dr. Sanda, this is Dr. Sandha. And remember, your mouth is the gate way to your health, so take care of it in the most natural and best way possible.