Founder Stories: George Hatsopoulos, Founder of Thermo Electron

4 Oct 2022 · 116 min
1:55:40

In this extensive interview, George Hatsopoulos recounts his upbringing in a politically active, academically distinguished Greek family from the mountain town of Karpenisi, his wartime experiences under Nazi occupation, and his early fascination with tinkering—building a projector at age six and a short‑wave radio to listen to the BBC despite German prohibitions. He describes how these formative experiences fostered an entrepreneurial mindset, leading him to study at MIT after winning a scholarship, where he received unprecedented institutional support for his thesis on thermionic energy conversion—a concept of generating electricity by boiling off electrons from heated iridium. Hatsopoulos founded Thermoelectron in 1956, initially developing the thermionic converter, securing a NASA contract for space power, and later pivoting to artificial‑heart technology funded by NASA revenues. He explains Thermoelectron’s unique corporate structure: nurturing young engineers in a shared culture, spinning out ventures while retaining majority ownership, and emphasizing culture over size. He contrasts American entrepreneurial culture with European conservatism, discusses his long tenure teaching at MIT, his philosophy of rule‑breaking for purpose, and reflections on leadership, mentorship, and maintaining a balance of fun and work. The interview also touches on later challenges, including market fads, personal health issues, and his ongoing commitment to founding new companies under the same model.

Chapters

More from Joshua

youtube.com

Scientist Stories: Jennifer Doudna, The Code Breaker

10mo ago
youtube.com

Founder Stories: Helmy Eltoukhy, Founder & CEO of Guardant Health

1y ago
youtube.com

Scientist Stories: Fabian Theis, Machine Learning and Systems Biology

2y ago
youtube.com

Scientist Stories: Thomas Lanyon-Hogg, Chemical Biology in Drug Discovery

2y ago
youtube.com

Founder Stories: Bobby Gaspar, Manufacturing Hematopoietic Stem Cells

2y ago
youtube.com

Scientist Stories: Dana Pe'er, Single-Cell Gene Regulation

2y ago
youtube.com

Scientist Stories: Hans Waterham, The value of phenotypic assays in peroxisomal disorders

2y ago
youtube.com

Scientist Stories: Michael Rosenblum, Exploring Regulatory T-Cells

2y ago
youtube.com

Scientist Stories: Hannah Mitchison, Expanding Ciliopathies

2y ago
youtube.com

Scientist Stories: Leonardo Ferreira, Engineered Immune Cell Therapies

2y ago
youtube.com

Scientist Stories: Joel Zlotogora, Genetic carrier screening programs for reproductive purposes

2y ago
See all content