Gary Brecka explains that NAD is in every cell and does two things: it converts calories into ATP energy, and it gets consumed by enzymes that handle metabolism, stress, and DNA repair. The question now is how to replenish NAD+ after it depletes.
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NAD, nicotinamide adenine dinucleotide, is in every single cell in your body, and it has 2 jobs. The first job is energy. Every calorie you eat, whether it comes from fat, carbohydrate, or protein, has to pass through NAD on its way to becoming ATP, which is the energy currency of your cells. Without NAD, that conversion doesn't happen. The second job is how that NAD gets used. There are enzymes in your body that eat it. The proteins that regulate your metabolism and how your cells respond to stress, they run on NAD. The enzymes that repair damage to your DNA burn through NAD every time they go to work. So the hype was never about whether NAD+ matters, because it clearly does. The hype is about how you get it back.