How To Master The Learning Process With Naveen Jain

This is an interview with entrepreneur Naveen Jain about mastering learning through intellectual curiosity, the growing role of individuals/private companies in driving innovation (versus nation-states), and early-science claims linking health and aging to gene expression and the human microbiome (notably the abundance of microbial genes vs human genes and discussion of ApoE4 variability).
Chapters
Anyways, so your strategy for learning things, your strategy for learning things so you.
Know, it's about staying intellectually curious. So to me, the day you stop becoming intellectually curious is the day you die. So the only way you essentially are alive is you're constantly learning. So it's never about taking the horse to the water and making a drink. It's about making them thirsty. So the way I look at the life is that every single person, if you can inspire them to be intellectually curious, you have created a society that will always be learning and moving forward. The other part that I really like is that there has never been a time in the human history where individuals and small group of people are able to make an impact. That could only be done in the initially kings and the queen and the aristocrats and then later came by these nation states and superpowers. The same things that were done by the nation states and superpower are now being done by individuals and a small group of people. Whether it's going to space, it's no longer done by the nation states, is being done by private companies. Whether it's Elon or Richard or Jeff, they're all going out and doing things that would never be done. NASA did not invent reusable rocket. It's the private companies that innovate because they constantly have the reason to be cheaper, better, faster. Same thing we started to see in other areas of the industries. Healthcare. Healthcare is not going to be solved by Obamacare or Trump care or Putin care. It's going to be solved by some entrepreneurs saying enough is enough and we're sick and tired of the system that's constantly victimizing the humanity. When pharmaceutical companies have become parasite on humanity, the humanity must come together to kill the parasite. And that's exactly what is going to happen. Our education system will have to be completely rethought and reimagined that is designed for teaching new skills. And now we're living in the world of exponential technologies where any skill that you learn becomes obsolete by the time you actually graduate. And you have to completely rethink about learning to learn, learning to be able to solve problems, learning to be multidisciplinary rather than unidisciplinary because problems tend to be multidisciplinary, not unidisciplinary. And coming back to how I learned is that I tend to go deep into the subject when I'm starting a company. So in this particular case, when I started on the company all about human health and we really want to Understand? Why is it that people get sick, why is it that people die, why is it that people age? And ideally comes down to is that it can't be your DNA because your DNA never changes. Your DNA is always the same from the time you're born to the time you born.
DNA is a computer program essentially made up of Alphabet letters. That's exactly.
So your DNA is really the Alphabet that can write any story you want it to. And your RNA is really the story that's being written. So it's not the genes, the story.
That you can write, or that anyone else can write based on the idea that our own electrochemical signals that we produce, based on more quantum physics principles, can actually affect the other way people think and feel and believe.
Absolutely true. So I mean, you know, there's a whole lot more of the things. What I was trying to say was that, that your genes are not your destiny, it is. The gene expression is what your destiny is. And when you start to think about your gene expression, there's something that I never knew, which is if you look at just the number of cells in the human body, we have more microbial cells in our human body than the human cells. That means the cells you get from your mom and dad are less than what we essentially acquired after we are born and through these microbial ecosystem. But that's really nothing. What's really interesting is that human DNA only produces about 20, 22,000 genes. When it comes to the microbes primarily living in our gut, they produce 2 million to 20 million genes. That means at best we are 1% human. That means all the genes that are expressed in our body, less than 1% come from human DNA. And that's really interesting that if our gene expression is what makes us who we are and we have completely ignored the largest organ in our body and that was a big breakthrough for me.
Well, not only have we completely ignored it, but I mean, I'd argue we to a certain extent damaged it. Right. I mean, back to that old friends hypothesis I mentioned earlier. The whole idea behind that is that we have wiped out friendly species via our era of post industrialized antibiotic use and antibacterials that have rendered us microbially deplete to a certain extent and.
Absolutely correct. But I want to also hit on the point in a little bit more nuanced way. It's not necessary that our microbes need to be what they used to be in the past or they need to be in something. You know, if you look at the AB origins or the People living on the Amazonian forest, they have a very different microbes and they have very different set of DNA mutations. And we can essentially get a little bit more into science if you want. Now for example, in the modern human DNA, we believe if you have larger copies of a DNA called Apoe4, people believe that it associated with chances of getting Alzheimer's disease.
Alzheimer's, yeah, to some extent Alzheimer's and cardiovascular. You know, I'm a carrier the foe three, four. Right. So I am four four. You make decisions a month. You don't need as much saturated fat.
However, what they found is very interesting that people who are living in the Amazonian Forest have 6, 8 copies of Apoe 4 and they never get an assignment. An interesting thing is that gene also tends to be extremely protective gene against infection. Since they have lot of these insects and stuff parasite that cause infection. ApoE4 actually protects them from these bacterial.
Infections similar to like the sickle cell anemia gene.
Exactly.
Against malaria for mosquitoes.
So sickle cell was designed to essentially protect you from malaria. And now people essentially can today obviously, you know.
Sensitivity and to some extent a lot of the other.
More from Jeffrey

The Solution to Aging Might Be Closer Than Anyone Realizes - With Ben Goertzel









