A short YouTube talk (by Jeffrey Jaime, CISSP) that links practical recovery practice—cold water immersion—to reduced delayed-onset muscle soreness and improved training/recovery, then shifts to methylene blue where the speaker summarizes proposed neuroprotective and memory-enhancing mechanisms at low doses (mitochondrial electron cycling, enhanced cellular respiration, antioxidant effects) while warning against high doses due to SSRI-like activity.
Chapters
Think about it this way. If cold water immersion blunts muscle soreness, which we know that it does, limits muscle soreness, it limits delayed onset muscle soreness. If that allows you to train harder the next day, or the next, throughout the next week, etc. Then you could make a case that the pros outweigh the cons, right? Or maybe you just enjoy it and you feel good the rest of the day after you do it. And you're not lifting weights to put on as much muscle as possible. You're lifting weights to feel good. And the cold water makes you feel even better after you work out. Then proceed. Methylene blue is interesting. It goes into the memory enhancing and neuroprotective mechanisms of action of methylene blue. So at low doses, not very, very high dosages because it is a what's called a selective serotonin reuptake inhibitor. You don't want to mess around with super high doses of methylene blue, but it has been shown to be beneficial as an electron cycling in the mitochondrial electron transport chain, enhancing cellular respiration and antioxidant properties, leading to improved nervous system function. It's been shown to assist with memory consolidation and cognitive enhancement.