Ketones work differently depending on context. After exercise, ketones plus carbs and protein boost mTOR activation for muscle growth. But in longevity studies, ketosis combined with calorie restriction actually lowers mTOR, which may extend lifespan.
That's one thing about ketones that I love, is that it's almost like an adaptive fuel, because we have seen in studies with opposing effects. For example, we have seen an increase in leucine mediated MTOR activation when you take it after exercise with carbohydrate and proteins.
Leucine mediated MTOR activation. If you take ketones after exercise with regards to protein, what you mean is have, like, an anabolic effect.
Anabolic recovery. Yeah. And then if you look at longevity studies that has calorie restriction and ketosis, they are looking at decreasing in MTOR activation.
Right?
Right. Same thing with.
The grail of longevity, which drives me nuts, because you get all these people wasting away muscle. I'm like, you want to be, like, hard to kill as you age. You don't necessarily want to chase calorie restriction at all costs.
The Solution to Aging Might Be Closer Than Anyone Realizes - With Ben Goertzel
