Beyond Hot Flashes: The Hidden Impact of Menopause with Karen Martel

15 Dec 2025 · 77 min
Episode

15 Dec 2025 · 77 min

0:00

A JJ Virgin podcast episode (Beyond 40) interviewing Karen Martel about perimenopause and menopause: causes of midlife weight gain, the roles of declining progesterone and estradiol (and later testosterone) in metabolic changes, impacts of toxins and SHBG on hormone availability, limits of diet/exercise alone, benefits and timing of hormone replacement therapy (start in perimenopause rather than waiting one year post-period), practical HRT approaches (cycling, transdermal estradiol and progesterone, topical estradiol for skin), cautions about high/steady progesterone dosing, importance of testing plus symptom-guided care, and use of low-dose GLP-1s as an adjunct for weight loss when hormones and lifestyle are optimized. The episode also includes product mentions (Karen’s hormone creams with a JJ10 discount) and a user guide to HRT.

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