Can Eating Fish Cause Heart Disease?
15 Dec 2025 · 11 min
Dr. Steven Masley explains that fish doesn't cause heart disease, but high TMAO levels (a compound your gut bacteria produce from choline and carnitine) raise heart attack risk by 62%. He recommends cold-water fatty fish like sardines and wild salmon two to three times weekly, and warns against high-mercury fish like grouper, tuna, and swordfish.
Questions this episode answers
July 16, 2020
Two to three times per week (cold-water fatty fish preferred).
About 62% higher risk of heart attack, stroke, and cardiac death.
Large tropical/high-mercury fish such as grouper, tuna, bass, swordfish, and shark.
Chapters
Hey, J.J. here. Can you believe how fast the holidays are knocking at the door this year? One minute it's pumpkin spice season, the next you're getting your guest room ready and wondering where their wrapping paper went. And that's when I turned to Wayfair. From bedding and towels to holiday decor and last minute stocking stuffers, Wayfair has everything you need to get your home and holidays together fast. And for way less. With Wayfair, I know I can refresh my guest room in no time. Maybe I'll add a soft new comforter or a few holiday throw pillows. With Wayfair, it's so easy and everything arrives super fast. Plus, there's free shipping for any order over $35 easy and total peace of mind. So whether you're hosting, gifting, or just adding those final festive touches, Wayfair has your back. And when the holidays wind down, Wayfair has everything you need to tuck it all neatly away. Smart storage solutions for every room from the kitchen to the closet. Get organized, refreshed and ready for the holidays. For way less head to Wayfair.com right now to shop all things home. Wayfair Every style, every home. That's W-A-Y-F-A-I R.com hey, it's JJ here. You know, I've been talking about environmental toxins forever, and laundry detergent is a sneaky one. A lot of them contain harsh chemicals like dyes, preservatives, and even UV brighteners. Those brighteners don't actually clean anything. They just coat fabric so your eyes think things look whiter or brighter. That's more chemicals I don't want on my family's sheets or skin. And if you've got sensitive skin or allergies around the house, this can be a big problem. That's what got my attention about Earth Breeze. It looks like a dryer sheet, but it's actually laundry detergent. You toss one in the washer and that's it. No pouring, no mess, and no heavy plastic jug. Their packaging is lightweight cardboard, which helps reduce plastic waste. And if you choose the fragrance free option, it's gentle, hypoallergenic, non irritating and non sensitizing. I really like how simple it is and how fresh and clean everything comes out without those unnecessary chemicals. Right now you can try Earth Breeze for up to 40% off with free gifts@earthbreeze.com virgin that's earthbreeze.com virgin for up to 40% off plus free gifts on your first order saving on your education should be a right, not a competition. At University of Phoenix, you'll get the best scholarship or savings you qualify for. Simple as that. Explore scholarship options at University of Phoenix Can Eating Fish Cause Heart Disease? This is JJ Virgin, four time New York Times bestselling author, celebrity nutrition expert, and Fitness hall of Famer. I've been on a lifelong quest for answers to the toughest health questions, and now I'm sharing what I found with you. Welcome to Ask the health expert. We112 on Instagram asks. I've been reading that fish increases tmao, which has been found in the most severe cardiovascular cases. Should I be eating fish? Hey, it's JJ and I've got Dr. Steven Masley, physician, chef and nutritionist and Author of the 30 Day Heart. Tune up to answer. Stay with me. Hey, it's J.J. here. Now let's be honest. The holidays are basically a financial ambush. Travel, hosting gifts, surprise holiday school things. Suddenly you're wondering how December turned into a spending spree. If you want to keep your finances under control this holiday season, you need to be using Monarch. It's rated the Wall Street Journal's best budgeting app of 2025. Monarch is the all in one personal finance tool that brings your entire financial life together in one clean interface on your laptop or your phone. What really grabbed my attention is how fast those little holiday expenses pile up with Monarch. Seeing everything in one place makes it a lot harder to accidentally overspend, and honestly, I appreciate anything that keeps me from starting January with a money hangover. You'll love exploring the holiday spending category. Imagine how good it will feel to actually see what's happening before your credit card statement does that whole dramatic reveal thing. Monarch basically shows you exactly where the money is going in real time, and that level of clarity could change everything, right? Don't let financial opportunity slip through the cracks. Use the code virgin@monarch.com in your browser for half off your first year. That's 50% off your first year@monarch.com with code Virgin Ray Ban. Meta glasses come with open ear audio so you can listen to your favorite music without blocking out the world around you.
Hey Meta, Play Gorgeous.
Here's Gorgeous by Doja Cat. You can also ask Meta AI questions.
Hey Meta, when's Doja Cat's next concert?
Doja Cat is playing at the Los Angeles theater next Tuesday. Sweet Ray Ban Meta Glasses available at Ray Ban stores and other authorized retailers.
As people have been reading that fish increases TMAO levels, which are associated with Cardiovascular disease. The short answer to that question is no. Let me be clear. Fish does not cause heart disease. And almost all the studies showing that people who eat fish at least two to three times a week especially, let's be clear, cold water, fatty fish like sardines, wild salmon, sole, mussels, those sources of seafood or fish do not cause heart disease. In fact, actually they prevent you from having a heart attack or stroke. But let's get to the TMAO part of this because that's an important concept that's new and I think is worth addressing. Tmao. Trimethylamine oxide is a compound produced from an amino acid like choline or carnitine, which are predominantly in the highest source of them is in red meat, but they're also in poultry and fish. And trimethylamine oxide, they've done studies and they've shown in people who have super high levels or, you know, the top 20 percentile, has 62% more heart attack, stroke and cardiac death than people who have low levels of tmao. So TMAO actually probably is more important than your cholesterol level and for your risk of cardiovascular disease. But it's much more complicated than that. Just comes from carnitine and choline as amino acids in food. TMAO is produced from these amino acid compounds, but they depend on specific strains of bacteria in your gut. Firmicutes bacteria. Now, an interesting thing is if you eat lots of red meat and you don't eat fruits, vegetables, beans, nuts, olive oil, red wine and vinegar, you produce bacteria, firmicutes bacteria that makes lots of tmao, increasing your risk for heart disease. But they've shown that if you follow a Mediterranean diet or a vegan diet and don't eat any meat, poultry or dairy or beef, if you are following that kind of diet, you don't make that kind of bacteria. So even if you took some carnitine or choline as a supplement, you wouldn't make nearly as much TMAO than if you ate a red meat diet and didn't eat the Mediterranean vegetable and olive oil and red wine that go with it. So probably one of the more effective ways of lowering your TMAO levels is either to be vegan, avoiding all animal protein products, or to follow a Mediterranean diet. In a Mediterranean diet, you can have poultry and seafood two to three times a week for each of them. You also eat a lot of vegetable, fruit, beans and nuts, olive oil, red wine, balsamic vinegar. All those things tend to lower TMAO levels and you can. The recent studies are actually testing probiotic supplements in particular to look at could we modify our gut flora, gut microbes, and we probably can. So I think in the near future we'll be looking at specific supplements to lower TMAO levels. They're being tested as I speak, but should you be eating fish? Absolutely. Fish contains long chain omega 3 fats which lower inflammation, decrease arrhythmias, improve your blood sugar levels and improve your cholesterol profile. So it's pretty clear that eating fish, especially cold water fish, is going to have a very nice improvement on your lipid profile and your blood sugar level and help decrease inflammation. All of which leads to lowering your risk for heart disease. I do caution you on eating big mouth more tropical fish, you know, that are high in mercury, things like grouper, tuna, bass, swordfish or shark. I would avoid those. Stick to cold water fish and make sure you follow a Mediterranean diet when you do that. Vegetable, fruit, beans, nuts, olive oil, red wine as all of those things help decrease the bacteria that convert to tmao. I hope that's helpful. I think it's safe to eat fish, especially when you're eating all those other food products. And I wish you the best of health.
This is JJ with Ask the Health Expert. I do this five times a week, so make sure you never miss a show by going to subscribetojay.com.
Toyota Thon is on, so stop by.
Your local Toyota dealer and test drive a spacious grand Highlander or ready for.
Anything RAV4 with great financing and lease.
Options available to qualified customers. Visit buyatoyota.com for more Toyota let's go places.
Hello listeners, this is Anne Bogle, author, blogger and creator of the podcast what Should I Read next? Since 2016, I've been helping readers bring more joy and delight into their reading lives. Every week I tag all things books and reading with a guest and guide them in discovering their next read. They share three books they love, one book they don't, and what they've been reading lately, and I recommend three titles they may enjoy reading Next. Guests have said our conversations are like therapy, troubleshooting issues that have plagued their reading lives for years, and possibly the rest of their lives as well. And of course, recommending books that meet the moment. Whether they are looking for deep introspection to spur or encourage a life change, or a frothy page turner to help them escape the stresses of work, school, everything, you'll learn something about yourself as a reader and you'll definitely walk away confident to choose your next read with a whole list of new books and authors to try.
So.
So join us each Tuesday for what Should I Read Next? Subscribe now wherever you're listening to this podcast and visit our website what Should I read next podcast.com to find out more.
More from JJ


Healthy Revisit: Heavily Meditated - Transforming Your Emotional Landscape with Dave Asprey






