JJ Virgin4x NYTimes Best Selling Author, Certified Nutrition Specialist, Fitness Hall of Famer

Heal Your Leaky Gut

2 Jul 2025 · 1 min

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1:00

In this segment of the "Heal Your Leaky Gut" interview, JJ Virgin asks the co‑host about practical steps for repairing intestinal permeability. The speaker outlines a three‑pronged approach: (1) cleanse the gut microbiome by addressing bacterial overgrowths and infections to avoid further barrier irritation; (2) provide targeted nutrient support such as L‑glutamine, zinc, omega‑3 fatty acids, vitamin A, and immunoglobulins to bolster gut lining and immune function; (3) promote the repopulation of beneficial microbes—particularly Akkermansia—while also managing stress, since cortisol can damage the mucosal layer. The discussion emphasizes a holistic, multi‑factor strategy rather than relying on a single leaky‑gut supplement.

Chapters

What are some of the things that you like to put in place to help heal the gut back?
Number one thing is we have to look at the microbiome piece and make sure that we're cleaning up the microbiome piece so we're not causing more irritation of that intestinal barrier. So bacterial overgrowths, infections, things like that. Then we can of course bring in targeted nutrient support. So sometimes L-glutamine is helpful. We can use things like zinc. Omega-3s can be great. Vitamin A can be great. Immunoglobulins are great for gut immune function. So those are some more kind of targeted strategies that we can bring in. And then of course supporting the, the regrowth of and the repopulation of those good gut bugs. Once, once again, going back to Akkermansia, like low levels of that can contribute to intestinal permeability. So we're— we take the approach of not just, oh, here, take this one leaky gut supplement, right? We're like, what is everything that's contributing to this breakdown in the intestinal barrier, including the stress piece? Because we know cortisol will poke holes in that mucosal layer of the gut lining.