How To Build Muscle Almost 2x Faster (NEW RESEARCH)
15 Dec 2025 · 22 min
This single-episode podcast (JJ Virgin — The Well Beyond 40) combines sponsor ad reads with an evidence-referenced guide to building muscle faster. JJ covers nutrition (protein with 2.5–4 g leucine to trigger mTOR; eat carbs around workouts), supplements (creatine, vitamin D + K2, fish oil/omega-3s, urolithin A/mitopure), hormonal considerations (thyroid, estrogen, cortisol) and training/recovery strategies (6–30 reps per set, multiple sets, 90–120s rest, progressive overload, 8-week cycles with a deload week). Recovery modalities discussed include sleep, sauna, red light therapy, cold plunges (timing caveat), massage, Epsom salt baths and foam rolling. JJ cites multiple studies (2013, 2015, 2016, 2017, 2018, 2021, 2022, 2023) to support claims and gives a realistic growth expectation (~1–2 lbs muscle per month). The episode also includes promotional segments for Earth Breeze, Wayfair, Monarch (Wall Street Journal best budgeting app of 2025), Corona, Dick's Sporting Goods, Toyota, and cross-promotion for other podcasts.
Chapters
Hey, it's J.J. here. You know, I've been talking about environmental toxins forever, and laundry detergent is a sneaky one. A lot of them contain harsh chemicals like dyes, preservatives, and even UV brighteners. Those brighteners don't actually clean anything. They just coat fabric so your eyes think things look whiter or brighter. That's more chemicals I don't want on my family sheets or skin. And if you've got sensitive skin or allergies around the house, this can be a big problem. That's what got my attention about Earth Breeze. It looks like a dryer sheet, but it's actually laundry detergent. You toss one in the washer and that's it. No pouring, no mess, and no heavy plastic jug. Their packaging is lightweight cardboard, which helps reduce plastic waste. And if you choose the fragrance free option, it's gentle, hypoallergenic, non irritating, and non sensitizing. I really like how simple it is and how fresh and clean everything comes out without those unnecessary chemicals. Right now you can try Earth Breeze for up to 40% off with free gifts@earthbreeze.com virgin that's earthbreeze.com virgin for up to 40% off plus free gifts on your first order. Hey, JJ here. Can you believe how fast the holidays are knocking at the door this year? One minute it's pumpkin spice season, the next you're getting your guest room ready and wondering where their wrapping paper went. And that's when I turned to Wayfair. From bedding and towels to holiday decor and last minute stocking stuffers, Wayfair has everything you need to get your home and holidays together fast. And for way less. With Wayfair, I know I can refresh my guest room in no time. Maybe I'll add a soft new comforter or a few holiday throw pillows. With Wayfair, it's so easy and everything arrives super fast. Plus, there's free shipping for any order over $35 easy and total peace of mind. So whether you're hosting, gifting, or just adding those final festive touches, Wayfair has your back. And when the holidays wind down, Wayfair has everything you need to tuck it all neatly away. Smart storage solutions for every room from the kitchen to the closet. Get organized, refreshed and ready for the holidays. For way less, head to Wayfair.com right now to shop all things home. Wayfair. Every style, every home that's W A Y f a I r.com this episode.
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I'm JJ Virgin, PhD dropout. Sorry, mom turned four time New York Times bestselling author. Yes, I'm a certified Nutrition Specialist, Fitness hall of Famer, and I speak at health conferences and trainings around the globe. But I'm driven by my insatiable curiosity.
And love of science to keep asking.
Questions, digging for answers, and sharing the information I uncover with as many people as I can.
And that's why I created the well Beyond 40 podcast to synthesize and simplify.
The science of health into actionable strategies.
To help you thrive.
In each episode, we'll talk about what's.
Working in the world of wellness, from.
Personalized nutrition and healing your metabolism to.
Healthy aging and prescriptive fitness.
Join me on the journey to better.
Health so you can love how you.
Look and feel right now and have the energy to play full out at 100. Hey, it's J.J. here. Now let's be honest. The holidays are basically a financial ambush. Travel, hosting gifts, surprise holiday school things. Suddenly you're wondering how December turned into a spring spending spree. If you want to keep your finances under control this holiday season, you need to be using Monarch. It's rated the Wall Street Journal's best budgeting app of 2025. Monarch is the all in one personal finance tool that brings your entire financial life together in one clean interface on your laptop or your phone. What really grabbed my attention is how fast those little holiday expenses pile up with Monarch. Seeing everything in one place makes it a lot harder to accidentally overspend, and honestly, I appreciate anything that keeps me from starting January with a money hangover. You'll love exploring the holiday spending category. Imagine how good it will feel to actually see what's happening before your credit card statement does that whole dramatic reveal thing. Monarch basically shows you exactly where the money is going in real time, and that level of clarity could change everything, right? Don't let financial opportunity slip through the cracks. Use the code virgin@monimal.com in your browser for half off your first year that's 50% off your first year@monarch.com with code Virgin.
The holidays are almost here, but there's still time to score great gifts at Dick's Sporting Goods. Find everyone's must have gifts from Nike, FP movement, Adidas and more. Need your gifts fast? Stop by your local Dick's or shop Dick's.com for fast shipping, curbside pickup or same day delivery. Every holiday starts at Dick's. Building muscle can feel like watching grass grow, but there's some science back ways to make it happen faster. And the more you focus on the three major strategies I'm going to share in this video, the better your results. First up, you got to feed your muscles, I think about protein and carbs. Well first of all, protein's key because protein helps drive muscle protein synthesis. And we know from the work of Dr. Donald Layman that you need somewhere between 2.5 to 4 grams of leucine to trigger MTOR to trigger muscle protein synthesis. So you want to eat optimal amounts of protein for you. And I created a protein calculator and a free seven day protein challenge that you can get at JJBurgin.com seven day the number seven there was a 2016 randomized clinical trial in the journal Sports that found that having carbs before a workout helped athletes perform better. They performed better in short intense activities and also they felt less tired and their brains worked better which allowed them to react quicker and pay better attention during the exercises. I did a couple months where I was really testing out fasted versus non fasted workouts because there was so much buzz about fasted workouts. And I kept thinking, I don't know that this makes so much sense because really when you're doing intense workouts and if we're doing workouts to build muscle, we're doing intense workout, right? If you're doing intense workouts, you're really going to use more glucose and glycogen than you are fat anyway. So the whole point of fast workouts was you'd burn more fat. But I'm like, but I'm doing intense workouts and not really looking at burning fat. And if you really want to burn fat it really comes down to overall energy flux throughout the day. And you really want to think about eating around your workouts like an hour or two before and then after so that you're supplying your body what it needs in terms of carbs and protein to refuel. Your glycan stores the energy stores of carbs in your muscles. So so you can use Those to work out harder and that you've got the protein that you need to fuel muscle protein synthesis and refuel those amino acid stores. What about supplements? Because supplements can make a big, big difference. And the first one I have to shout out, of course is creatine. So creatine is going to boost muscle energy production during high intensity exercise. Creatine basically is part of phosphocreatine, which is what we use when those short, intense bursts of exercise. There was a 2017 literature review that was published in Current Prote and Peptide Science that showed that taking creatine supplements can help you build more muscle and get stronger. Because creatine increases the creatine and phosphocreatine in your muscles, which then helps regenerate energy during those intense workouts, which means that you can perform better during strength training, which leads to more muscle growth and strength over time. Another one you might not have thought about in terms of building muscle is vitamin D. But vitamin D is important because it helps with muscle protein synthesis, which is essential of course for building and repairing muscle tissue. It supports muscle function and strength by aiding in calcium absorption, which of course is critical for muscle contraction. And then I always take vitamin D3 with K2. And K2 plays a role in bone health, indirectly impacting muscle function and strength. Now together, these contribute to overall muscle health by helping maintain muscle mass and function and supporting recovery after exercise. There was a 2017 non randomized controlled trial that was published in Biogerontology that looked at the effects of Nordic walking training combined with vitamin D supplementation on inflammation in elderly women. And what they did was they divided participants into two groups based on their baseline vitamin D levels. And the results showed a significant decrease in two pro inflammatory proteins in the group with higher baseline vitamin D levels. After the 12 week intervention, there was a rise in another protein called myokine orisin that was induced by exercise that indicated a potential anti inflammatory effect. So what the study suggests is that by combining training and vitamin D supplements mutation, you reduce inflammation in older women with better outcomes observed in those who had higher baseline vitamin D levels. Now, fish oil, fish oil is interesting because it also can be anabolic. First of all, we know that fish oil as an omega 3 can reduce inflammation, so it can reduce muscle soreness and inflammation potentially after workouts. But also omega 3 fatty acids, those are what are in fish oil, may enhance muscle protein synthesis, so could be anabolic. Fish oil supplements may improve muscle strength and function, especially in older adults, and enhance exercise performance by improving blood flow and oxygen delivery to muscles. Fish oil can also help prevent muscle loss during periods of inactivity or aging. So there was a study in 2013. It was a non randomized controlled trial published in the Journal of Nutrition that found that fish oil helps build muscle by improving the balance between muscle protein and DNA and increasing muscle protein mass. Fish oil activates important signaling pathways like Akt and Foxo which are essential for muscle growth and maintenance. And it suppresses pro inflammatory cytokines which can lead to muscle atrophy. So it helps preserve muscle mass. Another supplement that I love is mitopure. Mitopure from Timeline Nutrition is Urolithin A and it can increase mitochondrial biogenesis which means you're building new mitochondria in the cell. And improved mitochondrial function means better energy production within the muscle cells which could lead to increased endurance and performance during workouts. Plus, mitopure may reduce muscle damage and oxidative and allow you to recover more quickly between exercise sessions. Might appear also may support muscle growth and strength over time because it's promoting that mitochondrial health and its ability to enhance cellular metabolism could optimize nutrient uptake and utilization by muscle cells, which aids also in muscle building effects. Next up, let's make sure your hormones are helping you, not hurting you. Now you probably think hormones using testosterone, but you got to make sure that your thyroid is working optimally because thyroid hormones like we're talking T3, T4 are important for controlling how your body uses energy, including building and breaking down muscle proteins. Having your thyroid just right is key to keeping your muscles strong and healthy. These hormones have a big say in how your body burns energy and uses nutrients which directly affects how your muscles grow and mend. Bottom line is when your thyroid isn't doing its job properly, like if you've got hypothyroidism, you might feel weak, tired and have trouble making new muscle. So keeping your thyroid hormones in check is critical for making the most of your muscle building efforts. There was a study in 2018, it was an epidemiological analysis and it was published in the Journal of Endocrinology and it showed that thyroid hormones are important for growing, staying warm and keeping your metabolism working right. They also play a big role in how our muscles move, grow and get energy. To make all this happen, thyroid hormone needs to get around our body, which it does with the help of certain proteins and receptors in our cells. These proteins and receptors help thyroid hormone do its job. When your body needs thyroid hormone, it gets converted from one form, T4 to another T3 with the help of certain enzymes. T3 is like the boss when it comes to muscle movement and energy. It controls how your muscles relax and contract and helps them get energy from your food. The levels of thyroid hormone inside our cells are controlled by how much is converted into T3 and how much has turned into reverse T3, which is another, less active form. The balance of thyroid hormones inside our cells affects how our muscles repair themselves and grow new muscle cells. So having good thyroid function is a must for building muscle. Now, estrogen is another key player in keeping muscles strong and healthy. And by the way, I'm talking to women here on this one. Imagine your muscles as a house, with estrogen as the builder laying down the bricks. Without enough estrogen, your muscles might not be as sturdy or resilient. Estrogen matters even more for women when building muscle. It helps regulate the balance between building new muscle, that protein synthesis, breaking down old muscle. Having the right amount of estrogen is essential for women to achieve their muscle building goals and maintain overall strength and fitness. There was a systematic review that was published in 2023 in the journal Maturetis. And in this journal, the researchers looked at the role of estrogen in female skeletal muscle aging. And the study aimed to explore how estrogen deficiencies, such as in postmenopausal women or estrogen supplementation such as through estrogen therapy, affects skeletal muscle mass function damage repair in energy metabol. The review includes 32 studies and suggest that estrogen deficiency in postmenopausal women is associated with reduced muscle mass and strength. Estrogen appears to reduce markers of muscle damage inflammation in animal models and promote muscle repair and regeneration and also may protect muscles by working as an antioxidant to reduce oxidative damage, stabilize cell membranes by fitting between their fat layers and attaching to estrogen receptors, controlling the activity of various genes and targets. The other thing that's important, cortisol. Now, cortisol is your primary stress hormone and it can really mess with your muscle building goals. It can disrupt the delicate balance needed for muscle growth. When you're totally stressed out, cortisol acts like a signal to your body, telling it to tap into muscle tissue for energy. When it's stressed, it's like your body's emergency fuel. But the downside is that it can lead to muscle breakdown instead of muscle growth. So if you're constantly stressed, your body might end up breaking down more muscle than it can rebuild. And that's a problem if you're aiming to get stronger or gain muscle mass There was a study in 2021. It was a meta analysis published in the Journal of Clinical Endocrinology and Metabolism. And it looked at how cortisol levels affect muscle strength and mass. The researchers found higher cortisol levels were linked to weaker grip strength and linked to lower overall muscle mass, especially in women. Now, when they adjusted for fasting glucose, that whole thing was weakened, suggesting that glucose here might also be important. But the research provides insight into how cortisol could influence the development of sarcopen. Remember, sarcopenia is low muscle mass. You also have to do the work and in order to build muscle, you need volume. So you want to do six to 30 repetitions per set. You want to do multiple sets with about a 90 second to 2 minute rest break in between. When you're doing this, you want to also continue to progress. Here's the thing with exercise, it should never get easier. You're getting stronger. But in order for something to be exercise, you have to do more than what you're used to. So how do you continue to progress? You can add an extra set, you can add, add more reps, you can change the tempo, you can add another exercise. If you've got a very stable schedule, you can do eight weeks of a specific program where you're continuing to progress within that program, and then take a week, and it's called a deload, where you lighten your loads, you cut your intensity and volume and it kind of gives you time to mentally recover. It can reduce your risk of injury. So you can give yourself that little deload. I find when I travel, I kind of get some deloads in there, even though I didn't want them. So. But if you're at home and you find that you really can have a really great set schedule, that deloading can work really well. And again, it would be eight weeks of a very focused program where you're continuing to increase and improve and then take a week of going a little bit easier and lighter and then go back and hit it again. You gotta really dial in your recovery because your recovery is really where you're building the muscle. This is where you're repairing, this is where you're rebuilding. And sometimes this can be the hardest thing for us to do. Really critical here. As you do more intensity, make sure you're getting good sleep. Sleep is where we're raising growth hormone, recovering and repair pairing. And another thing that can be really helpful here is sauna. There was a randomized controlled trial published in 2022 in Biology of sport that found that a single post exercise infrared sauna session improved neuromuscular performance, reduced muscle soreness, enhanced perceived recovery without any detrimental effects on the autonomic nervous system. It supported great mood and supported readiness for working out again. Another one that can work well is red light therapy. There was a 2015 study that looked at using light therapy to see how it helped the muscle cells and it found that it actually improves mitochondrial respiration, which is great for energy production and great for enhancing exercise performance. The results were seen about three to six hours after the therapy. So go to the gym, come home if you have red light at home, great thing to do. Another thing that you can do that can help with recovery is cold plunging. However, there's a caveat with this. Whereas sauna and red light can actually be done after a workout and help, cold plunge actually can get in the way of muscle protein synthesis. When you work out, you're going to create some inflammation, that's actually a good thing. If you go and do cold plunging too soon, you can actually get in the way of that process. And while it might reduce inflammation, it might also reduce muscle protein synthesis. So with cold plunging, what I actually do is I will do cold plunging or cold shower in the morning before I go to workout. This is another one you can do to help recover. Massage, a great massage can help as well. There was another study that was published in the Journal of Physiology, found that compressive loading massage can help muscles recover, grow back and actually even change their structure if they've started to atrophy. So it's a very specific massage technique. But this massage technique can improve the size of the muscle fibers and help muscles actually make protein. So the other one that I really love here, besides this are, you know, Epsom salts bath. So I know not everyone has a sauna or red lights cold plunges. You can always get in a cold shower. So that works. But the one that I do love is a great Epsom salts bath and I will also use a foam roller and so perhaps can't get a massage, you can still use a foam roller or one of those home percussive units to achieve the same effect. Let's talk realistic expectations. Because typical rate of muscle growth, one to two pounds a month with the strategies I just gave you, hopefully these will take you to the higher end of that and what you measure, monitor, you can improve.
Be sure to join me next time for more tools, tips and techniques you can incorporate into everyday life to ensure you look and feel great and are built to last. Check me out on Instagram, Facebook and my website jjvirgin.com and make sure to follow my podcast at. Subscribe to JJ.com so you don't miss a single episode. And hey, if you're loving what you hear, don't forget to leave a review.
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Helping me reach more incredible women just like you to spread the word about aging powerfully after 40. Thanks for tuning in and I'll catch you on the next episode. Hey JJ here. And just a reminder that the well Beyond 40 podcast offers health, wellness, fitness and nutritional information that's designed for educational and entertainment purposes only. You should not rely on this information as a substitute for, nor does it replace professional medical advice, diagnosis or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.
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