How to Shift Your Body Weight Set Point with Dr. Sara Gottfried

15 Dec 2025 · 32 min
Episode

15 Dec 2025 · 32 min

0:00

Podcast episode in which JJ Virgin interviews Dr. Sara Gottfried about the brain–body connection to weight regulation. Dr. Gottfried introduces the concept of an "adipostat" (a hypothalamic fat-regulating thermostat or body-weight set point), explains factors that push the set point toward weight gain (sugar/refined carbs, alcohol, gut permeability, toxins like glyphosate, stress), and highlights strategies to shift the set point: improving metabolic flexibility and meal timing (endorsing time-restricted eating/16:8), stabilizing blood sugar, reducing inflammatory foods/toxins, exercise, stress control, and progressive approaches to fasting. The episode also mentions an 18-question quiz tied to the book Brain Body Diet and includes sponsor ad segments and a listener Q&A about managing hunger while starting time-restricted eating.

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