I’m Interested In Adding Supplements to My Health Routine. Where Should I Start?
15 Dec 2025 · 13 min
Sean Wells recommends starting with formats you'll actually take, then adding a B-complex, probiotic with prebiotics, creatine (1-1.5g daily), vitamin D3 with K2 (5,000-10,000 IU depending on sun exposure), and dihydroberberine twice daily. Consistency matters more than perfection.
Chapters
Hey, it's J.J. here. You know, I've been talking about environmental toxins forever, and laundry detergent is a sneaky one. A lot of them contain harsh chemicals like dyes, preservatives, and even UV brighteners. Those brighteners don't actually clean anything. They just coat fabric so your eyes think things look whiter or brighter. That's more chemicals I don't want on my family sheets or skin. And if you've got sensitive skin or allergies around the house, this can be a big problem. That's what got my attention about Earth Breeze. It looks like a dryer sheet, but it's actually laundry detergent. You toss one in the washer and that's it. No pouring, no mess, and no heavy plastic jug. Their packaging is lightweight cardboard, which helps reduce plastic waste. And if you choose the fragrance free option, it's gentle, hypoallergenic, non irritating, and non sensitizing. I really like how simple it is and how fresh and clean everything comes out without those unnecessary chemicals. Right now you can try Earth Breeze for up to 40% off with free gifts@earthbreeze.com virgin that's earthbreeze.com virgin for up to 40% off plus free gifts on your first order. Hey, JJ here. Can you believe how fast the holidays are knocking at the door this year? One minute it's pumpkin spice season, the next you're getting your guest room ready and wondering where their wrapping paper went. And that's when I turned to Wayfair. From bedding and towels to holiday decor and last minute stocking stuffers, Wayfair has everything you need to get your home and holidays together fast. And for way less. With Wayfair, I know I can refresh my guest room in no time. Maybe I'll add a soft new comforter or a few holiday throw pillows. With Wayfair, it's so easy and everything arrives super fast. Plus, there's free shipping for any order over $35 easy and total peace of mind. So whether you're hosting, gifting, or just adding those final festive touches, Wayfair has your back. And when the holidays wind down, Wayfair has everything you need to tuck it all neatly away. Smart storage solutions for every room from the kitchen to the closet. Get organized, refreshed and ready for the holidays. For way less, head to Wayfair.com right now to shop all things home. Wayfair. Every style, every home that's W a Y F A I R.com the holidays are almost here.
But there's still time to score great gifts at Dick's Sporting Goods. Find everyone's must have gifts from Nike, FP Movement, Adidas and more. Need your gifts fast? Stop by your local Dick's or shop Dick's.com for fast shipping, curbside pickup or same day delivery. Every holiday starts at Dick's.
I'm interested in adding supplements to my health routine. Where should I start? This is JJ Virgin, four time New York Times bestselling author, celebrity nutrition expert and fitness hall of famer. I've been on a lifelong quest for answers to the toughest health questions and now I'm sharing what I found with you. Welcome to Ask the Health Expert. Nora from Instagram asks, I'm interested in adding supplements to my health routine. Where should I start? Hey, it's JJ And I've got my buddy Sean Wells with us today to answer this question. He is the world's leading nutritional biochemist and expert on health optimization. He's formulated over 500 supplements, foods, beverages and cosmeceuticals and patented 10 novel ingredients and now is known as the ingredientologist. That means the scientist of ingredients. Formerly, he was a chief clinical dietitian with over a decade of clinical experience and he's counseled thousands of people on innovative health solutions such as keto, paleo, fasting and supplements. He's also personally overcome various health issues including Epstein Barr virus, chronic fatigue syndrome, fibromyalgia, depression, insomnia, obesity and a pituitary tumor. As a world renowned thought leader and author on mitochondrial health, his expertise can help any health conscious individual to better manage stress, experience higher performance and gain energy through utilizing his practical research based solutions. And his new book is called the energy Formula. You want to grab that? He's also an action sci, fi and fantasy nerd who loves Spartan races. All right, we'll be right back with the answer, so stay with me.
Hey, J.J. virgin here. Okay, real talk. So often the holidays sneak up on me, travel, gifts, hosting, you know, all the things and suddenly it's like, wait, who spent what and where? And I know I'm not the only one who's looked at a bill in January and thought, wow, that escalated quickly. If you want to keep your finances under control this holiday season, you need to be using Monarch. It's rated the Wall Street Journal's best budgeting app of 2025. Monarch is the all in one personal finance tool that brings your entire financial life together in one clean interface. On your laptop or on your phone, Monarch lets you link everything and gives you real time visibility so you're not shocked later. Right now I've been checking the holiday spending category so I don't accidentally start the new year with that dreaded debt hangover. And honestly, just seeing everything laid out is already helping me stay more aware. This season, Monarch does the heavy lifting. It links your accounts in minutes, gives you smart categorization and super clear visuals. Yes, that end of year reset could be a real goal. This time. Don't let financial opportunity slip through the cracks. Use the code virginonarch.com in your browser for half off your first year. That's 50% off your first year@monarch.com with the code Virgin.
This episode is brought to you by Pacifico. Here's a story you've probably never heard. Legend has it, decades ago, a couple surfers went down to Mexico in search of epic swells, but they found something unexpected instead. It was still crisp, lively and smooth, but it had nothing to do with waves. It was Pacifico, a delicious Mexican lager. It's like it was brewed to be discovered. Pacifico find your own way 21+discover responsibly Pacifico Clara Beer imported by Crown Import, Chicago, IL.
Great question. Where do you start? If you're starting basically from the bottom or the basics with supplements and your health routine, Great question. The biggest thing is going to be what are you going to use every day? What are you going to make a part of your lifestyle? If you have 10 supplements that each are supposed to use four capsules a day as part of their serving, are you going to take 40 capsules a day? I can, but I don't know if you will consistently. So what matters is that you do it consistently, that you have compliance just like medications. And you know when people don't take their medications, they're not going to get results and in fact they can even be dangerous. That won't be the case here, typically with supplements, but you won't get the benefits. So think about the format that you'll take, what works for you. That's going to be critical. Maybe some of these have to be in a powder form and some of them will be in capsule form. Is it the size of the capsule that will work for you, et cetera. So getting into some of the supplements that I would recommend. An active B vitamin, multivitamin is going to be important. One that has the active Bs. It's also called coenzymated B vitamins. Things like P5, P for B6, methylcobalamin for B12, 5 methyltetrahydrofolate for folic acid. They're in their active forms. This saves you the enzymatic steps of converting them. And some people have issues like the MTHFR gene in doing so. So that's really important, that you get the energy and the benefit of your multivitamin by getting the more active form. Next up, I would recommend a probiotic supplement that also has prebiotic short chain fibers in it, things like fos gos. There's one called pre4pro, that's a phage that helps build up more bacteria, good bacteria in the gut. That's called probiosis versus dysbiosis, which means your gut has too much bad bacteria. And you want to make sure that the probiotics are in microencapsulated or spore form, meaning they're stable and they're protected. Because typically probiotics are very susceptible to damage from light, heat and moisture. So I've found that the microencapsulated or spore forms are best. Moving on. Okay, so creatine, you've probably heard of this, you think it's for bodybuilders, you think it's for guys trying to get big, so on and so on. But they've actually shown creatine in smaller doses, like a gram to a gram and a half a day is going to help with bone health, reproductive health, brain health, like literally helping against Alzheimer's, Parkinson's, traumatic brain injury, et cetera. And people function better on it. It's a really good methylator, protecting you from cancer and DNA damage. And yes, it will help with your strength, your muscle mass maintenance as you age, protecting you from sarcopenia. So creatine is a huge one that I support. Moving on. Vitamin D3, you might already have some in your multivitamin. It's not enough and it's not in the right form. It's probably in a dry form. And the oil form is much better, much more absorbable. So vitamin D3 is going to be superior as the oil. So make sure to get about 5 to 10,000. I use a day of the vitamin D3 and also get vitamin K2 in the MK7 form with it. That's going to help protect you from calcium, which actually can be counterproductive if you're not getting the D3 and K2 with the calcium, you can actually cause calcification of arteries and it can be counterproductive. With the vitamin D3, it's best to get your blood levels checked. I would say 5,000 is a decent amount if you're not getting much sunlight. And 10,000 would be if you're not getting much sunlight at all. 5,000 would be if you're getting some sunlight. So that would be, you know, something that I think about. I use about 5000ius with about 50 micrograms of K2, so those are going to be some big ones. On top of that, I recommend dihydroberberine. So this is a really active form of berberine that's about 5 to 10 times more bioavailable than berberine. And it lasts about twice as long in the plasma, so you only need to take it twice a day. Berberine has been shown to be superior to metformin head to head. And this form, dihydroberberine, is better than berberine. So what's really cool is it's potent against anti aging, especially with glycation, which is blood sugar damage. And we all tend towards insulin resistance. We tend to put on body fat easier as we age, we tend towards inflammation, we tend towards something called advanced glycation end products. And that's that blood sugar damage that literally that acronym means ages. And it does age you. And that's why metformin is one of the most powerful, not only diabetic drugs, but most powerful anti aging drugs. And so dihydroberberine is something that I would recommend that everyone take because it's the most powerful thing I know of to protect you.
This is JJ with Ask the Health Expert.
I do this five times a week, so make sure you never miss a show by going to subscribetojay.com.
Foreign.
Toyota Thun is on. So stop by your local Toyota dealer and test drive a rugged Tacoma or full size Tundra with great financing and.
Lease options available to qualified customers.
Visit buyatoyota.com for more Toyota let's go places.
Hello listeners, this is Anne Bogle, author, blogger and creator of the podcast what Should I Read next? Since 2016, I've been helping readers bring more joy and delight into their reading lives. Every week I take all things books and reading with a guest and guide them in discovering their next read. They share three books they love, one book they don't, and what they've been reading lately. And I recommend three titles they may enjoy reading next. Guests have said our conversations are like therapy, troubleshooting issues that have plagued their reading lives for years and possibly the rest of their lives as well. And of course, recommending books that meet the moment, whether they are looking for deep introspection to spur or encourage a life change or a frothy page turner to help them escape the stresses of work, school, everything. You'll learn something about yourself as a reader, and you'll definitely walk away confident to choose your next read, with a whole list of new books and authors to try. So join us each Tuesday for what Should I Read Next? Subscribe now wherever you're listening to this podcast and visit our website what Should I read next podcast.com to find out more.
More from JJ


Healthy Revisit: Heavily Meditated - Transforming Your Emotional Landscape with Dave Asprey






