Overcoming Estrogen Dominance with Magdalena Wszelaki

15 Dec 2025 · 35 min
Episode

15 Dec 2025 · 35 min

0:00

Podcast episode in which JJ Virgin interviews Magdalena Wszelaki about estrogen dominance: what it looks like (symptoms range from heavy/painful/irregular periods, fibroids, endometriosis, fibrocystic breasts, fat distribution, hot flashes, and links to estrogen-related cancers), how it can persist into and after menopause, and how genetics (COMT, MTHFR, BRCA) and estrogen metabolism (clean vs "dirty" metabolites) affect risk. Tests discussed include DUTCH and saliva/urine hormone/metabolite testing (blood tests are described as less informative). Management recommendations emphasized: an elimination anti-inflammatory diet (remove gluten, dairy, soy, eggs, reduce sugar), increase cruciferous vegetables and broccoli sprouts (sulforaphane), liver support (digestive bitters, castor oil packs), targeted supplements (DIM/sulforaphane, calcium D-glucarate, magnesium, vitamins C/E/A, zinc, vitex for progesterone support), and lifestyle (sleep, stress reduction, movement). Host and guest also mention resources: Magdalena's book Overcoming Estrogen Dominance, her quiz ("How estrogenic are you?") and a quiz landing page at jjvirgin.com/estquiz. Episode includes multiple sponsor ads (Earth Breeze, Wayfair, Monarch, Buffalo Trace) with brief promotional details.

Questions this episode answers

jjvirgin.com/estquiz

The DUTCH test (urine-based hormone/metabolite panel)

COMT (catechol-O-methyltransferase)

50% off the first year with code Virgin at monarch.com

90 proof, 45% alcohol by volume

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