The Brain Fog, Fatigue & Hormonal Birth Control Connection with Dr. Jolene Brighten

15 Dec 2025 · 41 min
Episode

15 Dec 2025 · 41 min

0:00

This podcast episode (part 2 of a series) features JJ Virgin interviewing Dr. Jolene Brighten about links between hormonal birth control and brain fog, fatigue, mood changes, metabolic effects, and long-term health concerns. Dr. Brighten describes proposed mechanisms (CoQ10 depletion, increased cortisol-binding and thyroid-binding globulins, insulin resistance, microbiome disruption, reduced B12, increased inflammation/CRP) and notes epidemiological findings tying hormonal contraceptive use to higher rates of depression and antidepressant prescriptions. The episode emphasizes testing and recovery: expanded thyroid testing (free T4/T3, reverse T3, TBG, TPO/Tg antibodies), cortisol profiling (saliva or urine/DUTCH), DHEA-S, fasting insulin/glucose, HbA1c, CRP, plus gut and liver support. They contrast synthetic hormonal contraception with bioidentical hormones (different doses and effects), discuss delivery methods, and give practical lifestyle and supplement guidance; free resources and Dr. Brighten’s book Beyond the Pill are promoted.

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