What Is the Best Berberine Form to Take, Typical Dosage, and Is It Safe to Use Long Term?

Hey, J.J. here. Can you believe how fast the holidays are knocking at the door this year? One minute it's pumpkin spice season, the next you're getting your guest room ready and wondering where their wrapping paper went. And that's when I turned to Wayfair. From bedding and towels to holiday decor and last minute stocking stuffers, Wayfair has everything you need to get your home and holidays together fast. And for way less. With Wayfair, I know I can refresh my guest room in no time. Maybe I'll add a soft new comforter or a few holiday throw pillows. With Wayfair, it's so easy and everything arrives super fast. Plus, there's free shipping for any order over $35 easy and total peace of mind. So whether you're hosting, gifting, or just adding those final festive touches, Wayfair has your back. And when the holidays wind down, Wayfair has everything you need to tuck it all neatly away. Smart storage solutions for every room from the kitchen to the closet. Get organized, refreshed and ready for the holidays. For way less head to Wayfair.com right now to shop all things home. Wayfair Every style, every home. That's W-A-Y-F-A-I R.com hey, it's JJ here. You know, I've been talking about environmental toxins forever, and laundry detergent is a sneaky one. A lot of them contain harsh chemicals like dyes, preservatives, and even UV brighteners. Those brighteners don't actually clean anything. They just coat fabric so your eyes think things look whiter or brighter. That's more chemicals I don't want on my family's sheets or skin. And if you've got sensitive skin or allergies around the house, this can be a big problem. That's what got my attention about Earth Breeze. It looks like a dryer sheet, but it's actually laundry detergent. You toss one in the washer and that's it. No pouring, no mess, and no heavy plastic jug. Their packaging is lightweight cardboard, which helps reduce plastic waste. And if you choose the fragrance free option, it's gentle, hypoallergenic, non irritating and non sensitizing. I really like how simple it is and how fresh and clean everything comes out without those unnecessary chemicals. Right now you can try Earth Breeze for up to 40% off with free gifts@earthbreeze.com virgin that's earthbreeze.com virgin for up to 40% off plus free gifts on your first order.

Welcome to Walgreens. What can I help you with today?

Hi, I need a last minute gift for a secret Santa. Something thoughtful, impressive. Not a fruitcake.

We've got Ferrero chocolates, artisan coffees, even a spa kit.

Any vibe you're going for, whatever says wow.

This guy's great at giving gifts.

How about this premium skincare gift set? Just needs a bow. Will look like you planned it weeks ago.

Well, happy holidays, gifts, holiday decor, and more. The holiday road is long. We're with you all the way, Walgreens.

What is the best berberine form to take typical dosage and is it safe to use long term? This is jj Virgin, four time New York Times bestselling author, celebrity celebrity nutrition expert and fitness hall of famer. I've been on a lifelong quest for answers to the toughest health questions and now I'm sharing what I found with you.

Welcome to Ask the Health Expert.

Willow from Instagram asks, what is the best berberine form to take typical dosage and is it safe to use long term? Hey, it's J.J. and I've got my buddy Sean Wells with us today to answer this question. He is the world's leading nutritional biochemist and expert on health optimization. He's formulated over 500 supplements, foods, beverages and cosmeceuticals and patented 10 novel ingredients and now is known as the ingredientologist. That means the scientist of ingredients. Formerly, he was a chief clinical dietitian with over a decade of clinical experience and he's counseled thousands of people on innovative health solutions such as keto, paleo, fasting and supplements. He's also personally overcome various health issues including Epstein Barr virus, chronic fatigue syndrome, fibromyalgia, depression, insomnia, obesity and a pituitary tumor. As a world renowned thought leader and author on mitochondrial health, his expertise can help any health conscious individual to better manage stress, experience higher performance and gain energy through utilizing his practical research based solutions. And his new book is called the energy Formula. You want to grab that? He's also an action, sci, fi and fantasy nerd who loves spartan races. All right, we'll be right back with the answer, so stay with me.

Hey, it's J.J. here. Now let's be honest. The holidays are basically a financial ambush. Travel, hosting gifts, surprise holiday, school things. Suddenly you're wondering how December turned into a spending spree. If you want to keep your finances under control this holiday season, you need to be using Monarch. It's rated the Wall Street Journal's best budgeting app of 2025. Monarch is the all in one personal finance tool that brings your entire financial life together in one clean interface on your laptop or your phone. What really grabbed my attention is how fast those little holiday expenses pile up with Monarch. Seeing everything in one place makes it a lot harder to accidentally overspend, and honestly, I appreciate anything that keeps me from starting January with a money hangover. You'll love exploring the holiday spending category. Imagine how good it will feel to actually see what's happening before your credit card statement does that whole dramatic reveal thing. Monarch basically shows you exactly where the money is going in real time, and that level of clarity could change everything, right? Don't let financial opportunity slip through the cracks. Use the code virgin@monarch.com in your browser for half off your first year. That's 50% off your first year@monarch.com with code Virgin.

Ray Ban Meta Glasses come with open ear audio so you can listen to your favorite music without blocking out the world around you.

Hey Meta, play Gorgeous. Here's Gorgeous by Doja Cat.

You can also ask Meta AI questions.

Hey Meta, when's Doja Cat's next concert? Doja Cat is playing at the Los Angeles Theater next Tuesday.

Sweet Ray Ban Meta Glasses available at Ray Ban stores and other authorized retailers.

Great question on Berberine. I get this all the time. If you look up my name Sean Wells on Google, one of the top hits is berberine. I have been talking about berberine for years because I've been talking about keto for 20 years and I've been talking about berberine for probably about half as long. It's one of the most potent anti aging anti diabetic pro ketone insulin sensitivity. Improving it improves amp K protects you from advanced glycation end products and glycation which is blood sugar damage. This is such a powerful compound as is its kind of drug equivalent metformin. And so anyone associated with having diabetes or insulin resistance definitely is interested in metformin or the herbal equivalent berberine. But certainly people that are into anti aging and looking to lower inflammation with CRP, lower hemoglobin A1C, the blood sugar and live longer are taking things like berberine or now the new form that I was involved in the patent of called dihydroberberine. So what's cool about dihydroberarine is it's about five to ten times more bioavailable so it increases much more in the plasma at a much lower dose. You only have to take about 100 milligrams versus 500 milligrams of berberine. And also what's really cool is it lasts about twice as long in the plasma versus standard berberine. So standard berberine, you're taking 500 milligrams three times a day. And with dihydroberberine, you're taking around 100 milligrams two times a day. So it's much more potent. It doesn't have the GI distress that's sometimes associated with metformin or berberine. Maybe about 20% of people get GI distress. So what's really cool is dihydroberberine doesn't have that. And you just take it before a meal, like around the time of the meal, and you will see dramatic changes. If you're tracking blood sugar again, whether you're diabetic or not, you can use like a CGM, a continual glucose monitor. Those are getting popular IVs, one. And you can see just how effective the dihydroberberine is, especially when you're having carbohydrate. But it's still going to help even if you're having a high protein meal or things like that. So highly recommend dihydroberarine. Its trademark name is Glucovantage. There are several products on the market coming out with it. But, you know, berberine is still a great product that for some reason you can't find that. I mean, I would recommend my number one supplement recommendation is berberine or dihydroberberine. It's the most powerful anti aging compound that I know of. I'm saying that dihydroberberine is superior, but it's still amazing to be on berberine. Here's an example of when I was formulating with berberine in a product with the past life of the company that I used to formulate for. I was on keto. I took the 500 milligrams of Berberine and was just testing both with and without the supplement. So at one point, I did a carbohydrate challenge with 75 grams of dextrose. And I decided to see how that would impact my blood sugar both with and without berberine. So without berberine, my blood sugar went all the way up to 199 in two hours. And with the berberine, this was like a week later doing the same thing with the berberine. I never got above 100 and I was already going back down at one hour. Dramatic, dramatic difference. So this is just a powerful tool. I'm not at all diabetic, not even close to insulin resistant, and I still use it every day and I feel like it's one of the most powerful reasons I'm 47 that I think I look pretty young and feel great. So definitely recommend Berberine or dihydroberber.

This is JJ with Ask the Health Expert.

I do this five times a week, so make sure you never miss a show by going to subscribetojay.com.

Hello listeners. This is Anne Boeckle, author, blogger and creator of the podcast what Should I Read next? Since 2016, I've been helping readers bring more joy and delight into their reading lives. Every week I tag all things books and reading with a guest and guide them in discovering their next read. They share three books they love, one book they don't, and what they've been reading lately, and I recommend three titles they may enjoy reading Next. Guests have said our conversations are like therapy troubleshooting issues that have plagued their reading lives for years and possibly the rest of their lives as well. And of course, recommending books that meet the moment. Whether they are looking for deep introspection to spur or encourage a life change, or a frothy page turner to help them escape the stresses of work, school, everything, you'll learn something about yourself as a reader and you'll definitely walk away confident to choose your next read, with a whole list of new books and authors to try. So join us each Tuesday for what Should I Read Next? Subscribe now wherever you're listening to this podcast and Visit our website whatshouldireadnextpodcast.com to find out more.