Hormones Are the Secret to Entrepreneurial Success! | H&F #653

1 Apr 2025 · 50 min
50:05

Podcast episode (H&F #653) featuring Dr. Pamela Smith interviewed by Joe Fier about the central role of hormones in health, longevity and high-performance work. Dr. Smith explains key male and shared hormones (testosterone, estrogen subtypes, progesterone, DHEA, cortisol, pregnanolone, thyroid, insulin, melatonin), measurement methods, target/‘golden’ ranges, links between toxins and hormonal decline, and the complementary role of toxin-removal (therapeutic plasma exchange) plus personalized medicine and nutrition.

Questions this video answers

50 (units not specified) — Dr. Smith states 'the golden number for pregnanolone is 50 or above.'

Estrogen, progesterone, testosterone, DHEA, cortisol, melatonin (pregnanolone measured by blood).

About 0.35 to 2 (she recommends the lower limit of normal / near lower range as ideal).

Under age 60: 70–85 mg/dL; age 60 and above: 70–90 mg/dL (anything above 90 she flags as concerning).

6 (units not specified).

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