Novartis Buys Excellergy for $2B, Anthropic Vs. Pentagon, The Mansion Section | Diet TBPN

28 Mar 2026 · 31 min
Episode

28 Mar 2026 · 31 min

0:00

In this episode of the Diet TBPN podcast, hosts John, Jordi Hays, and Tyler discuss three main storylines. First, they break down Novartis’s $2 billion acquisition of stealth biotech Excellergy, highlighting the company’s focus on an IgE‑targeting allergy drug (EXL‑111), the classic biotech VC playbook, and the role of CEO Todd Zawodnick, a serial exit specialist. They also explore how AI is being used in pharma for FDA filing automation and trial acceleration. Second, they shift to AI news: a leak reveals Anthropic’s new “Mythos” model (part of the Capybara series), its claimed performance gains, pricing structure, and the broader impact on the AI compute market. They discuss Anthropic’s legal battle with the Pentagon over a supply‑chain risk designation, the pending injunction, and speculation about an upcoming IPO. Finally, the hosts move to the “Mansion” segment, detailing the sale of JFK’s former penthouse at the Carlyle Hotel, describing its historic significance and luxury features, and sharing anecdotes about ski‑in‑ski‑out homes with custom bars. Throughout, the conversation is informal, peppered with jokes, and interspersed with personal observations about polyphasic sleep, subscription economics, and industry hype.

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