Something Mini is Coming, Anthropic's $20B Round, Ackman’s Meta Move | Bryan Johnson, Andrew Huberman, Matthew Zeitlin, Joon Sung Park, David Risher, Todd McKinnon, Alexander Ksendzovsky

12 Feb 2026 · 218 min
Episode

12 Feb 2026 · 218 min

0:00

The episode is a fast‑paced, conversational podcast hosted by John Coogan with frequent contributor Jordi Hays. It opens with a quick news roundup (John Palmer’s viral piece, Anthropic’s $20 B funding, AI‑powered banking tools) before moving into a series of deep‑dive interviews. 1. Simile (Joon Sung Park) – The startup builds high‑fidelity human‑behavior simulations (“agents”) that Fortune‑500 firms can query for product‑launch, earnings‑call, and retail‑layout decisions. The founders explain their data‑collection pipeline, the role of game‑engine‑style worlds, their $100 M Series C raise, and how they differ from generic LLM fine‑tuning by focusing on irrational human preferences. 2. Lyft (David Risher) – Risher discusses record‑breaking Q4 results, the strategic importance of international expansion, the partnership with Waymo in Nashville, the logistics of AV depots, and broader market dynamics (energy, chip supply, OEM investment, regulation). He also reflects on how market reactions are now driven by bots that rewrite headlines. 3. Okta (Todd McKinnon) – McKinnon recounts Okta’s 17‑year journey from a Salesforce‑engineer’s side‑project to a $3 B identity platform, the first Andreessen Horowitz investment, the explosion of interest in AI‑augmented agents, and the emerging security challenges of prompt‑injection and over‑privileged agents. He speculates on the future of software engineering talent and the rise of cross‑silo agentic software. 4. Biological Computing (Alexander Ksendzovsky) – A neurosurgeon‑turned‑entrepreneur describes growing live neurons on a 5,000‑electrode plate, using them as ultra‑energy‑efficient analog processors, and two product lines: a plug‑in that accelerates video‑generation models and an algorithm‑discovery platform that extracts post‑Transformer principles from real brain activity. The company raised a $25 M seed round. 5. Caffeine & Yerba Mate (Andrew Huberman) – Huberman promotes his zero‑sugar, BPA‑free yerba‑mate drink, discusses caffeine’s performance‑enhancing effects, safe dosing, and its role in cognitive health. He also touches on bio‑hacking trends among elite athletes (vasodilators, peptides) and the regulatory landscape. 6. Throughout the show, the hosts sprinkle sponsor reads (Plaid, Vanta, Cisco, Graphite) and engage in light‑hearted banter (Super Bowl ad jokes, Golden Gate Bridge sponsorship). The episode ends with a rapid “Lambda Lightning” round and a final thank‑you. Key takeaways: simulation‑based AI is moving from research demos to enterprise‑grade decision tools; autonomous‑vehicle roll‑outs are still constrained by infrastructure, regulation, and financing; identity management is becoming the next cyber‑security moat as AI agents proliferate; biological computing promises orders‑of‑magnitude energy savings but is still early‑stage; and everyday performance‑enhancers (caffeine, peptides) are being scrutinized for both health and competitive advantage.

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