Jorge Cruise Podcast

14 May 2025 · 65 min

0:00

In this podcast episode, host Jorge Cruise interviews Dr. Jason Fung to challenge the traditional "calories in, calories out" view of obesity. Dr. Fung explains that body weight is regulated by a hormonal "thermostat" driven primarily by insulin and cortisol, which raise the set‑point, and by hormones such as GLP‑1, glycogen, and sympathetic‑tone activators, which lower it. He discusses how GLP‑1 drugs (e.g., Ozempic) and sympathetic stimulants (e.g., nicotine, historic Fen‑Phen) can shift the thermostat downward, leading to weight loss independent of calorie counting. The conversation covers the safety profile of GLP‑1 agents, their common side effects (nausea, vomiting, diarrhea), and the reality that they are not a magic bullet—proper nutrition and eating patterns remain essential. Dr. Fung compares the current enthusiasm for GLP‑1 drugs to past hype around bariatric surgery, noting both have efficacy but also significant drawbacks. He emphasizes that intermittent fasting and low‑carb, high‑fat diets naturally lower insulin, allowing the body to mobilize stored fat. The episode concludes with Dr. Fung sharing his online platforms (Twitter, YouTube, Medium) and recommending his book The Obesity Code as the definitive guide for listeners seeking deeper understanding.

Chapters

More from Jorge

1:37:38
Podcast

Cure Midlife Belly Fat | Dr. Jason Fung with Jorge Cruise

7mo ago
1:37:38
Podcast

Cure Midlife Belly Fat | Dr. Jason Fung with Jorge Cruise

7mo ago
16:23
Podcast

Rebuild Your Body in 8 Minutes

10mo ago
16:23
Podcast

Rebuild Your Body in 8 Minutes

10mo ago
20:40
Podcast

Why You Eat When You’re Not Hungry

10mo ago
20:40
Podcast

Why You Eat When You’re Not Hungry

10mo ago
10:39
Podcast

Turn Off Hunger

10mo ago
10:39
Podcast

Turn Off Hunger

10mo ago
0:23
Podcast

Jorge Cruise Podcast

1y ago
0:23
Podcast

Jorge Cruise Podcast

1y ago
1:29:17
Podcast

The Past Is F*cking You | Khalil Rafati with Jorge Cruise

1y ago
See all content