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I'm Marcelle Pick, I'm your host, and this is where we actually gonna dissect the complexities of modern medical advancements. And today specifically, we're gonna be delving into a highly topical issue in the world of medicine, the new generation of weight loss drugs. We're actually gonna focus on understanding the nuances which come out every day and long-term implications of treatments like the Ozempic, Mounjaro, and the newest Zepbound. So join us as we explore these groundbreaking drugs in great depth. So Ozempic was actually developed by Novo Nordisk and it has made headlines for its role in weight management worldwide alongside its original purpose for type 2 diabetes treatment. This actually led to the development of Wegovy, a high dose semaglutide specifically for obesity. However, an important aspect to consider is a long-term commitment these drugs may require, as studies to date have shown that about two-thirds individuals could regain their weight once they stopped using the medication. So there's a real rebound that occurs with this. So turning our focus on Eli Lilly's contributions, Manjari and Zepbound, the newest one to come to the market, we see a fascinating development in this field. So Manjari containing Triseptide has unique dualistic mechanisms. It not only mimics the GLP-1 hormones, which suppress appetite, but also the GIP hormone. And this dual action enhances effectiveness, which affects your blood sugar and aids in weight loss significantly. And eLilly leveraged this success to actually create Zepatier, a drug specifically for chronic weight management that also uses a tricyclic. And the key differences lie in Zepatier focuses on weight management, while Manjiri is primarily a diabetes medication with weight loss as its significant benefit. So these medications actually represent a significant leap, as you all know, in the weight loss treatment, yet they really come with a caveat. This is what I want you to pay attention to. The concern of weight regain is prominent with many facing the possibility of needing these medications indefinitely. And with the long-term effects still largely unknown, very important to remember, there's an area of uncertainty around their prolonged use. Now, the cost and availability of these medications also are really raising crucial questions. Their popularity, especially for off-label use, has driven up demand, affecting supply and raising significant ethical issues about access to these potentially life-changing medications. So addressing obesity, which is a condition influenced by so many factors, it's really clear that while medications like Ozempic, Mounjaro, and Zepbound can be part of a solution, they are certainly not the panacea, which is what everybody's saying they are. So we really need more of a holistic approach encompassing lifestyle changes, psychological support, and a sustainable long-term strategy. It's absolutely essential. So today's episode really brought us closer to understanding the nuanced world of these weight loss medications, but I'm here to tell you that they're not all that they were cut out to be. We know that if you don't change your diet, you'll actually have significant muscle loss. So increasing protein up to 30 grams per meal is crucial to maintain muscle mass. But what we see with these medications is that it also, for many, causes them to have a very significant distaste of food, which in the long run may not be sustainable. So really looking at lifestyle, we have to change our diet. We have to look at some of the psychological reasons that we might be eating so that we can and really understand that long-term weight loss is all about changing behavior. It's changing how you think about food. The wonderful thing these medications have done is it helps us understand that there are people that don't know what their full period is. They also are hungry all the time. So we absolutely need to have tools that will help them with this to be able to get their diet changed and to have long-term health benefits. If we don't change our diet, even if we lose weight and eat less, we're not getting healthier in the long run. So if you enjoyed this episode, stay tuned for more to come. And you can also follow us and share this with other people that you think might be interested in this.

This is Marcel. I want to introduce you to a concept that's just so exciting. So we know that the weight loss medications, semaglutide variety of medications, is very effective at decreasing your interest in food. The problem is that for many of you that you know that there are some side effects, and many of you that are watching this are seeing that you tried the medication and you didn't really feel very good on it, but you really wanted to lose that weight. The biggest problem I see in the weight loss industry in general is that so many people are hungry and they have cravings for these particular foods. So I created homeopathic drops that don't have significant side effects with nausea or problems with diarrhea or general GI discomfort. and what they do is they take the noise of food away, they suppress your appetite, and they really allow you the ability to be able to kind of sit back a bit and make some lifestyle changes and change your habits that are going to be the important thing long term. So for those of you that are interested, please look at the link below and it's marcel M-A-R-C-E-L-L-E-P-I-C-K.com and you'll be able to see a link there also for looking at the 21-day quick start, which is a 21-day program in which so many of my patients are losing weight very quickly and also being able to get the homeopathic drops there.