EP#76 - How to Add an Extra 5-10 Quality Years to Your Life with Dr. David Haase

You know, after the age of 28, all of us are dementing, all of us are Alzheimering. It just depends on what rate you're doing it at. And when is your brain going to degenerate faster than your body can maintain you. That is our current state of affairs. I believe we are entering absolutely into a time where that does not need to be the current state of affairs. The worst comorbidity, the worst corresponding disease to dementia is denial. Most drugs are well dosed poisons. It's an anti this, anti this inhibitor, that blocker of there. But when we're doing regenerative plasma exchange, we're creating an environment where the body does its job of healing with less inhibition and encumberment. It is the body that is actually doing the healing. I think of the most valuable thing in the world, most valuable thing that exists is wisdom. We cannot take relationship out of medicine. And relationship is a longitudinal story that is shared between a patient and a physician.

All right, this is going to be an emotional episode for me because my father is in late stage dementia. He's basically a shell. He went from being a strong, smart.

Functional guy to like a shell in a couple of years. My mom is, had Alzheimer's, it's slow for the past, I don't know how long. Now it's we noticed it six, seven years ago and both of them lived in a deep state of denial. And the guy I'm going to interview today, Dr. David Hazy, I met him seven, eight years ago. He's a client friend. Just love the man. He is in the business of giving you the one thing you buy, which is more time. Now if you just look at the genetic profile, I am going to either have Alzheimer's or dementia or both. It's just genetic, it runs in the family. So of course I'm on a search to prevent that. But also think about it like this. If you're listening to this and watching this podcast right now that Dan and I have been doing and also a member of, let's say Abundance 360, the number one thing people want to know about is longevity. So how could you buy an extra five or 10 years of quality time? And if you are more afraid of getting old and dying than death, this is really for you because that's the way I look at it. I'm not afraid of death. I had cancer eight years ago. I almost died. I know that pass. But dying is not pleasant. I wake up now, you know, every once in a while in pain and a couple of years ago started experiencing anxiety, a lot of pain in my shoulders and my joints. And it's like, what do you do about this? So Dr. David Hazi is a double board certified expert in regenerative medicine. He's been trained and he practiced at Vanderbilt and the Mayo Clinic. He's found a way to turn back your clock. Now his work is based on some cutting edge research in plasma exchange. And in the last 20 years he's taught over 10,000 physicians his systems. So if you're interested in life extension and increasing your productivity, your impact, enjoying life to its fullest, or giving that to someone who you love and care about, especially when you see it happening to them, this is going to be a great episode. So, Dr. Hazy, it's great to have you, sir.

Mike, it's a real honor to be with you. Having walked through how you've dealt with your parents. I just have tremendous amount of respect for you as a human being. And also there's a great deal of admiration for you as a coach and as a guy who's made a. Help me make a lot of very important changes in my life. So it's with just a deep amount of gratitude I get to be here with you today.

Thanks, man. This is, it's a pleasure. I've been so looking forward to this interview because.

You know, I'm around so many great entrepreneurs and I've also watched some of my legendary friends, I'm watching them die in decay and my parents. And also you look, look around and we, there are things we can do. And you had said something really profound. And I want to begin with the story of denial that you had. And then let's move into the how to reverse Aging and get into the science and the work we've been doing. But I think we really have to look at the impact first, which is if you're dealing with denial yourself or someone that you love, who you're around, that you can't get them to make that move and that really, it isn't our power, it's not what we need to do sometime, it might be part of our karma, you know, so to speak. But let's talk a little bit about denial first.

Yeah, wow. You know, memory loss, you know, we live in an information economy, right? We are our minds. And what we can do with our minds has become increasingly identified with who we are, our very capacity. So when we feel a threat to our identity, it's maybe even something that we don't believe we can do anything about. You know, we have to go into fight or flight or. But if there's not an enemy that's there.

The natural cognitive approach is to deny that it's a problem, you know, to shut it down, to stop the stress somehow by saying, oh, I'm just getting a little older. Oh, you know, I just had a senior moment. Oh, I'm, you know, just not quite as sharp as I was. Oh, you know, there's so many euphemisms that we use for this process of dementing and dementing. You know, dementia is. Yeah, we have. It's a disease. Alzheimer's is a disease. But really it's the process that we should be most interested in. We are. You know, after the age of 28, all of us are dementing, all of us are Alzheimering. It just depends on what rate you're doing it at. And when is your brain going to degenerate faster than your body can maintain you. That is our current state of affairs. I believe we are entering absolutely into a time where that does not need to be the current state of affairs. And dedicated a lot of years of my life to helping figure out this multifactorial causation of dementia. And the worst comorbidity, the worst corresponding disease to dementia is denial. And that's the one we have to deal with first.

All right, so let's move to the magic solution, because there's no such thing as magic. And I'd love to have some magical unicorns and sprinkly fairy dust as much as the next guy. However, there's some fascinating science here. So let's just begin with this great technology. It's something that is well known, it's based on science. And you also have some great stories and some programs that you've been involved in. So let's just do the big reveal. First of all, tell people what is this thing that you've been doing that's shown remarkable.

Success both with people who do have degenerative diseases like Parkinson's, like Alzheimer's, but also for a high performing entrepreneur or business owner who wants more higher quality life regeneration, mental acuity, increase in our sex drive, our mental drive, and our ability to just live longer, better.

Yeah. So actually, I think you are correct. It is magic.

What I think is magic.

I wanted you to say it, not me.

Yeah, no, it's okay. Yeah, it's absolutely right. Because when you can say, consider the body's intelligence and what we do, I mean, we take this food we put into our mouth and then it becomes us. It becomes a manifestation. And to Me, this miraculous intelligence which made the body and what continues to heals the body, I mean, that's as magical as it really gets when you really step start to think about it. And that magic is the creation of health in our bodies. It is stem cells and the stem cell satellites that do this job of continual repair, regeneration, rebuilding, of bringing us back to a youthful state. And this technology is technology that improves the functioning of the stem cells that are in your body, that are in your tissues, where the work actually has to happen. And this technology is called regenerative plasma exchange. Regenerative plasma exchange is a modification of therapeutic plasma exchange where that has been used for many years in treating severe autoimmune disease. This is a standard medical procedure, often only done inside of hospitals, often costing over $10,000. A procedure having a. But it has a well known side effect profile. It has a well known history. But the remarkable thing is because of the studies of parabiosis, which we can go into.

We now recognize that this is a way to bathe our stem cells in a more healthy cellular habitat. And as a result of that, have those stem cells start to do their job of regeneration and reproduction pair in a way that they used to have the potential to do.

So I think the big promise here is a combination of age reversal and neuroregeneration. And what I'd like to do with you, Dr. Hazy, is let's talk first about the mouse studies and the rat studies and where this science came from. And then I want to dive into a real life example with a real life patient of yours. Is that fair?

Yeah, sounds great. Sounds great.

Okay, go for it.

All right, well, mouse, let's talk about this first. Michael and Irina Convoy at Berkeley did this very interesting study where they took cloned mice. Only one was old, one was young. And they did a surgical procedure where they connected their skin side by side. So two little mice were running around the cage together. In a week, a remarkable thing happened. That old mouse started to turn young. We started seeing hair regrow in better. Muscles that were injured, recovered faster. The cardiac output improved. Osteoblasts, which are the cells that make bone, started to be stimulated. Immune function improved, and most remarkably, neurogenesis ensued. That means new brain cells started to sprout out.

Wow.

Absolutely amazing. But I learned new brain cells. What?

I want new brain cells.

I know.

So does everyone. Yeah, exactly.

All we need is a. Is a. Is a young clone of you and we can surgically. No, no, we're not.

That's.

That's not the treatment plan, and then.

The vampires come and then. Okay, yes. Okay, so we can't do that. But there is a legal alternative that does not require a clone sacrifice. I like where you're going here. All right, so the bottom line is you saw the mouse, you saw the rat. The old rat gets young, and the young rat presumably starts to get old, too.

The young mouse is actually poisoned by old. We don't think of old as being toxic. But the plasma of old stunted the stem cells of that young mouse, body wide, it did recover. And after they both lived about another month or so, they're separated out. And the young mouse lived to its normal expected lifespan. The older mouse lived closer to the expected lifespan of the young mouse. Now, there's not a lot of studies in longevity in parabiosis, but it has a remarkable.

Reasonability because if you can get body wide stem cells to function better, guess what, you're going to age more slowly and have far more likelihood to live longer.

Okay, so now we're going to harness that for people. And I know you've got some real life examples of patients you've worked with. So let's begin with. And you and I have had multiple conversations about this because when we started working together and I started telling you about what was going on with my parents, you said, well, let me tell you a couple stories. So one of them was this guy who you have a history with, but he had Parkinson's. So I'd like to know, you know, a little bit of his background. What, how his, you know, what happened to his life, what the situation and circumstance was, and then what happened after the procedure.

Yeah. Harry is a wonderful patient and friend of mine. He has been incredibly supportive of the progressive work we've been doing over the years and feel very proud that his Parkinson's has really not progressed. In the last six years we've been working together. And as we understood how this plasma exchange has a potential to treat dementia, he said, hey, can that help my Parkinson's? I want to be the first to go here. And he was one of our very first patients.

But he was a very engaged individual. But I didn't realize how much he had withdrawn from his life and he really was not living vibrantly because I don't get to see people at home. I see them in the clinic. And so we did our plasma exchange procedure, which is.

Takes about two and a half hours, and everything went fine. He went home. The next week, his wife calls back and she said, this is remarkable. He started gardening again. He hasn't gardened for many years. He's gone to board meetings at the business that he owns. He hadn't been to a board meeting in years. He's asked me out on dates, and his erectile function is improved. What happened?

And it really shocked me, frankly, because I was looking to do this to be something that is wise. I always think of this regenerative plasma exchange for treating dementia and neurodegeneration. Kind of like Stephen Covey. Right. It's important, but maybe not urgent. I'm seeing the urgency now, but I didn't expect it to make a difference acutely. And as we've been treating more and more patients and we're looking at especially cognitive function and improvement in executive function, increased sharpness and also improved performance after improved recovery after exercise have been some pretty consistent findings.

Okay, so we've got. We went from mice to people, in this case Parkinson's, and then let's talk a little bit about.

Memory and Alzheimer's and also a little bit about some of the clinical trials and also your observations then. And then we're going to get into, hey, we're the entrepreneurs who want more, we want to perform better, we want to have more, more, more. What's it take? And we'll get into the details. So for. If you're watching this going, okay, what about me? What about me? We'll get there, I promise.

That's right. You know, the.

When we saw that there's neuroregeneration happening in these mice, you immediately start to say, wow, how could that affect these conditions that currently have no known treatment, Alzheimer's and has no known treatment that, well, excuse me. There's been a long time since we've had even a new drug, but they don't do much.

And so if we can mimic this parabiosis, we have the potential to stimulate production of new neurons. So studies were done in animals to see if this was likely to work. And yes. And so a large trial was engaged called the Ambar trial. And this is nearly 500 patients with Alzheimer's disease of both mild and moderate severity.

This was multinational, multicenter, randomized, placebo, controlled blinded trial. And what was found is that in over 14 months in this study, the people who had moderate dementia had 61% less decline than the same individuals with moderate dementia that got placebo. 61% decline over 14 months is astounding. But then when you went to look at the individuals who had mild dementia or mild Alzheimer's disease, which I really think is there's no such thing as mild Alzheimer's disease in the real life world. Those individuals actually had some improvement in their memory, improvement in their executive functioning, and improvement in their behavior compared to when they started in the 14 months. So there was actually some reversal of neurodegeneration in that subgroup. And they certainly did not have the progressive decline that was seen in the placebo group. So those are amazing study. And they didn't just do these neurocognitive tests to check and see how well can you pay attention and all those little brain games. They also did tests of the proteins that are in the fluid around the brain, the CSF. They showed that phosphorylated tau and beta amyloid 42 fragments normalized in the CSF. By cleaning out the blood somehow we also cleaned the csf. Then they also did tests looking at FDG PET scans. They were able to show that the metabolism of the brain degenerated less when people got plasma exchange than if they were on placebo. So a biochemical, a metabolic, cognitive, behavioral, functional outputs all pointed towards the effectiveness of this and effectiveness at a level that was really meaningful. Not just a statistically significant, but a clinically significant change.

All right, and if we boil all that nerd talk down into some simple succinct entrepreneur proof sentence, it comes down to both reversal and.

Regenerative in a clinical environment. But that means consistent, reasonably predictable results, it appears, so far. Is that fair enough to say?

That is fair enough to say. When you clean the blood, the cells work better. When you have a healthy cellular habitat, the stem cells can behave at a younger phenotype. Essentially, they remember how they did their job when they were younger, when they are in a younger environment. We see this with us humans too, right? You're hanging around some young people, you start to act younger. It's no different for your stem cells.

Yep, you can't get much done if you're swimming in a toilet. So let's move. I couldn't help it. I couldn't help it. All right, let's talk about higher performance and getting more done as an entrepreneur and a business owner. And there's an old quote, don't know who originally said it, but a healthy man has many wishes, a sick man only one. And as a former cancer patient and now survivor, full disclosure, I've got half a colon, half a rectum.

And I function fine. And I survived. Okay? I'm perfectly happy. But I gotta be really, really careful about what I eat and how I perform. And I don't absorb Like I used to. So there's a whole bunch of new lifestyle things I've had to accommodate because of that. And the truth of the matter is, if I would have had proper testing and I was watching my lifestyle, there's a genetic component to this, but also stress, et cetera. There was just a lot of components here. I believe that I could have prevented a lot of this pain along the way.

And also moving forward, what I'm experiencing as an entrepreneur, which many of us. So you hit your 50s through your 70s and it could be younger or older, but you start waking up and aging sets in. So sore shoulders, knees, sleep patterns, increase in anxiety, noticeable depression, unless you're starting to take hormone replacement therapy, which I do now. I've noticed a huge difference and I think I've slowed the aging.

But in my case it is inevitable I will have.

Alzheimer's or dementia because it runs in the family and it has on both sides. Okay. So I mean I'm looking at the mirror in front of me when I see my parents unless I get some kind of an unfair advantage. Now that may not be true, but I do quarterly blood tests and results. And I'm only talking about me because my suspicion is our listeners and viewers here are going to relate to most all or some of what I just shared. And we want to help our parents or people around us and being able to give them good information and solutions. And for us it's like, how do we keep and get that unfair advantage and not go through the inevitable decline of aging? I'd rather just drop dead. I'm more afraid of aging than I am of death. So help us, Dr. Hazy. What does it take to do this thing and how long does it take when to get results? And then I think I'd like to talk about money too, if that's okay with you.

Absolutely. So I think it's important to when you ask, okay, well how does this work? It's really the body that's doing the healing. And this is what's super important. This is different than taking a drug for some that most drugs are well dosed poisons. It's an anti, this inhibitor, that blocker of there.

But when we're doing regenerative plasma exchange, we're creating an environment where the body does its job of healing with less inhibition and encumberment. And that's a really important understanding to put together there because it is the body that is actually doing the healing. When we think about the process of how does somebody engage and make that difference in their life. You know, we mentioned already denial. First of all, you have to admit that there's a problem and aging is a problem unto itself and recognize that this problem of dementing or Alzheimering has already started and the time to take action is now. So putting those pieces together, we recognize that your lifestyle makes a massive difference. If your plasma, if we can improve the health of your stem cells and therefore healthier brain and healthier tissues, and slow the degenerative thrust by removing out your old plasma and putting in regenerative factors, you can actually do some of that yourself too. I mean, this is, this is you exercising and eating well and bringing good food into your body and decreasing the toxins that come in your body. Regenerative plasma exchange is accelerated common sense in some ways because we're enabling this huge behavioral challenge which is cleaning up our lifestyle to be done in a chair in some ways. So how that would take place. The procedure itself takes about two and a half hours. An IV is placed in, two big IVs are placed in. Blood comes out, one side gets mixed with an anticoagulant and then that goes through a centrifuge and we pull apart the plasma and the red blood cells. And then those red blood cells are then mixed with an optimized replacement fluid. And it may actually have regenerative factors that are put in. There's tremendous amount of customization that goes in according to what are the things that are inhibiting you and what are the things you need to have that can increase your self healing capacity. And then that blood, that new mixture is brought back into the body and that's the real the process. And we can remove anywhere between 2 and a half and 5 liters of plasma at a sitting. Makes a big difference how big a boy you are. And that then gives the opportunity to have a clean environment to help have healthy stem cells.

Okay, so let's turn that into the practical tactical. How often should I do it? Is it this a one time thing? Is it something that should happen on a regular basis? How often? Like can you give us a roadmap if, you know, if you were going to give me a recommendation. 54 year old guy, previous cancer I've got, I just broke my collarbone. I'm actually mending that right now. Probably the worst pain I've ever felt in my life, by the way. Worse than cancer. It was a son of a gun. It's only a couple weeks. I was, but I, you know, and so breaking bones at a later age absolutely blows. But I'VE also, I've got a torn rotator cuff damage, you know, a little bit of damage in my shoulders. And I've. There have been times I wake up in pain. Right. And I do. I've been doing hormone replacement, which has made a huge difference. I don't walk by the mirror in the morning and go, ugh, like I did for a little bit. But you know, let's just say that, or let's look at a 70 year old, 70, 75 year old. But depending on where you are. So let's just say normal decline, but you want to maintain or reverse. What would your recommendations be?

Yeah, so the most important recommendation is get one done.

And do it soon. I mean, because degeneration continues long term, how frequently people need to have it done. We're gathering data to make better decisions on that. My guess, from the data that we have thus far, I think we can optimize the relatively healthy person that is dealing with all the other multifactors of health and disease. Once a quarter, I think would do an amazing shift for people and even once every six months, but absolutely annually. And again.

This is a very young science. We have the most experienced center, we have done this the most of any place in the United States on an outpatient basis focused on regeneration. And we're continuing to customize the programs for people according to what frankly their need is. We don't want to have over treatment.

But we don't want to have under treatment either.

I know you want a simple answer, don't you? You want me to say take four and you know, do this once a quarter and you know, Mike, two pills.

At night, two pills in the morning and pay me this much money. Yeah, I understand. But I'm also trying to make it easy for you too, for people who are listening going, yeah, I want to be optimized. And what anyone wants right now is certainty and you know, the price and they're going to do, you know. So the way I would present this to a business owner is imagine if a moment you could perform at 55 or 65 like you did at 35. And I don't know if that's possible. You know, I'm not trying to make claims here, medical claims or any other kind of claim. And the investment was X. So yes, what you're saying is do it once first. And like, let's say I go in and I'm going to do this. So I'm committed to doing this, but I come in and I do the treatment. You say it's two and a half hours in the chair. And am I going to feel different right away or like the next day or the next week? And how long can I expect to feel that difference, that incremental change? Let's just play. Let's pretend.

That's awesome, Mike, because we've had the.

Opportunity to hear who you are and we know what your desires are. So I would say once every six months would be ideal, given what we already know about you and your circumstances. But you really shouldn't expect to feel dramatically different from a standard albumin plasma exchange. However, there's so many things that we do to augment this process that yes, energy should be improved, cognition, improves.

Recovery in exercise. We've noted that happening repeatedly. We noted that we improve the microcirculation. We have a device in our office. It's really only one of 60 in the US and we can measure individual red blood cells going through the capillaries. And we can show that we can.

Improve this blood flow in the system.

It's a remarkable thing to see.

Perfusion improve, which then improves every stem cell that happens in the body.

For you.

Coming in and doing this.

The reason we don't have much of this available is that plasma exchange really only exists in hospitals right now. This is an in hospital intervention. It doesn't have to be because it can safely be done in the outpatient setting given the right parameters. But in the hospital, it's up near $10,000. As far as being billed towards insurance for doing one of these procedures, we drastically brought that price down to 5,000 and hoping to going lower than that. And then we have this amazing.

Opportunity to ask a question.

What are the underlying factors that are driving me forward not just to do plasma exchange, but to start recognizing what are the other factors that are increasing the frequency by which my body currently needs a cleanup?

You know, Mike, you don't feel.

You don't feel the effects of an oil change when you do it in your car. And that's the basic plasma exchange model.

But.

You don't really have an oil change that I know of right now.

That can fix the engine as it's flowing through. And that's really the opportunity here.

Got it. So it sounds like part of this is we all reach that threshold of aging when the decline becomes very rapid.

And there's no turning back. So some of this is maintenance. But also what I'm hearing you say is in addition to the plasma exchange, that you're doing some other additional treatments along with that that improve other various Parts or what you didn't say, but you and I have had these conversations before. You've got a whole wealth of different resources and tools that you employ, depending on the specifics of the body, the person, their age, and their background.

Absolutely. We have various depths at which we can investigate patients. I mean, I have patients of mine that are up at like, a quarter of a million dollars to tell. They tell me, do everything that we need to, to make certain that I have found every needle in my haystack. And so we have over 30 labs from across the United States, multiple researchers, multiple collaborators, and really have the ability to go all the way up to that. Creating a virtual, private medical center for a person, two individuals that come in and say, you know, I just want plasma exchange done. And I need to recognize that this has benefit. Everybody gets evaluation for safety, and we ask people to engage in gathering information so that we can improve the care of everybody that comes after them. So we're highly committed to.

Optimizing this process, but also making it available.

It is a real challenge. It is a technique that requires a lot of technology, a lot of training, a lot of specialized personnel. It's going to be quite an endeavor to make this widely available, but we're doing our very best to make that possible.

Okay, well, I know after again, spending a lot of time with you, I'm in. I'm going to do it. I'm going to come down to Nashville and go through the process. But I also want to get a little more specific when we talk about what this is. So this parabiosis now is parabiosis. Is that the thing that we're talking about, like the mice experiment dealio, or what exactly is that?

Right. Parabiosis. It just means life side by side. And so that is just the mouse experiments. So when you take the mouse experiments and you try and extrapolate them out to how can you mimic something close to this in humans? That's what you use therapeutic plasma exchange for.

Okay. And the benefits that we're aware of that have been measured in the past, that both anecdotally and scientific.

You know, what have they been? I want to get a little more specific again for my entrepreneurial mind. And also I know I'm going to get a whole bunch of questions from people who hear this, and they're either going to reach out and ask these questions, or I'm going to answer them on the podcast right now.

So I think basic science is what we get to lean on here, because this is such a fundamental property of living systems to need nourishment and have their toxins carried away. And that's what plasma does. So we're able to do animal experiments to give us a lot of insight here. So in the parabiosis idea, the question was, are we actually getting our benefit from bringing something really good into the body, or are we getting our benefit from taking out the bad stuff from the body? It turns out the answer appears to be both, because you can do mouse experiments of both types, either mimic this plasma exchange and remove the plasma from an old ratio, and that seems to have benefit for them. And that benefit, as I'll kind of repeat, is that, you know, the stimulation of osteoblasts to make new bone to improve the satellite cells inside the muscle to encourage repair that's faster and more efficient after injury. That's huge. That translates out into better improvement after exercise.

They saw the reversal of fatty liver disease. Fatty liver disease is an epidemic proportion in our world at present, Largely because of diet, but also because of just aging makes the mitochondria not function as well and get worse. And they also saw neurogenesis kicking in. So we saw that the changes happen to stem cell behavior Based upon just exactly how much.

Of an environment was provided that was healthy. And that's really the fundamental understanding of why we can regenerate the body from changing out the plasma, from changing the cellular habitat. We can make tremendous differences body wide.

Okay, so I'm gonna sum up what I believe I'm hearing here Just again, I wanna create a good container for folks. Now, I'm committed to coming down and doing this. And I presume what I'll do is I'll have some blood tests before. Cause I wanna see if I notice or see changes. I'll do some blood tests before I come down. I basically get hooked up, Two and a half hours later, the treatment's done. And we'll probably do some other things in addition to the plasma exchange. Is that fair to say?

Absolutely. So we have a correct.

Okay. And then let's say I get committed Because I want to make this an annual thing. I want to get my oil changed on a regular basis. And I want to increase performance, decrease pain, and decrease the speed of aging. And if I'm committed to this, based on what you know about me, two times a year would be adequate. Is that.

Without knowing kind of what your blood viscosity is, microcirculation, and what are the underlying factors that are causing that? Again, this is an exceedingly safe procedure. The way that we do it. And every time you think of an intervention, you really have to ask the question, okay, what is the risk versus benefit? And the risk of plasma exchange historically has come from these very large central catheters that get put in to a major vein in the neck. We don't use those. We use peripheral IVs so that we're able to drastically decrease the likelihood of infection or any other problems.

And so that risk versus benefit ratio, as long as we can keep the risk down, then.

The potential for benefit with repeat exchanges can be more appreciated.

Okay. All right.

Well, again, my objective, you know exactly what that is. And I'm reading between the lines here, which are entrepreneurs, business owners, higher quality of life, longevity, lower chance of aging or slower aging or some form of age reversal. That is our objective here.

And the expenses, again, they vary, but it sounds to me like it's well under $10,000 per treatment.

And there's other variables.

That's correct. You know, when it comes to neurodegenerative disease, especially when you start thinking of what the cost of something like this is, a year in a memory care center can cost anywhere from 75 to $150,000. And that's for a year of not knowing your family. A year of not being able to really engage in any way that one used to think of as important in their life. To have lost one's wisdom, to have lost one's connections to the world, their knowledge. That's a terrible year to pay that much for. And I think as a perspective is, instead we start thinking of Alzheimer's treatment as an investment. Just keep your years.

The years you have left at a high functioning state plasma exchange for a year is much less than.

Living in a memory care center for that same year.

I'm so glad you brought that up because again, looking at this, so my dad, who.

Had a Bible's worth of jokes, played guitar until he couldn't, and I don't know how many hundreds of songs he knew, never played with music by heart, danced.

In the small town I grew up in as a barber. He knew so many people, their histories, their children, it could always rattle him off. We couldn't walk through the local mall without everyone knowing. Bernie the barber and all that disappeared in three years. And it's unbelievably painful, so. And again, the same thing with my mom. And there was a possibility of hope. And yes, the cost of that memory care facility where he's sitting around, he's basically a shell. There's the body of my dad, but he ain't in there any longer. Right. And it is just a horrible experience. So for someone who's got an aging parent where you're noticing this, now is the time to investigate this as well, especially if you can have that conversation before they say, well, it's too late for me, or they're in denial. Like, he fought to the bitter end.

Just wouldn't acknowledge it. And part of it is he had a strong personality and a big identity, and he just didn't want to show that weakness until, you know, he couldn't take care of anyone, including himself. Or he started driving to church and he. Did he get lost? We ended up putting a GPS in the car and, you know, he just started wandering around and he got to the point where he came in and he finally cried and he said, I get lost. And then he'd wake up at three in the morning, dressed up, ready to go to church. You know, his whole big ritual is going to church every day to sing in choir or to just go there for a service. And it just got to the point where he'd leave and come back sometimes an hour and a half later, sometimes 15 minutes later, and didn't know where he was or he didn't recognize the highways any longer. And I don't want to end on a negative, sad note here, except I wanted you to be on the show and I wanted you to be here because I think what you're doing is so super important and to bring both hope and a possibility to the living and the aging is incredibly valuable. And again, I think it answers that question that so many people ask, is they're so interested in longevity. And I think this is a smart place to begin. So I don't know where you want to go from there, but I do want to ask you if you have any other comments based on what I just said. And then finally, where do people go to learn more about you and the clinic and make an inquiry or even schedule a visit?

Yeah. Well, I'll say the first part. I always forget to say how to find me. So I'll say, find us at maxwellclinic.com m a x w e l l clinic.com for maximizing wellness. And we'll take it from there. We'll take it from there. We have information there. But.

I did that front because I'm pretty emotionally affected by your story.

I don't work with people with neurodegenerative diseases, really, because it's fun.

It's very hard because to be honest about this is to say we're going to face ongoing decline and slide.

We're going to look it in the eyes, damn it. You know what? We're getting past denial, damn it. We're going to muster up our courage, we're going to muster up our bravery, and we're going to say, this is what life is. This is how my brain is functioning. This is how my father's brain is functioning. This is what's going on. And it takes courage. And I have just huge respect. I've had huge respect for you as you've shared this over the years. And I have huge respect for the people who are struggling with this.

It is a profound opportunity. One of the things reason I do this is I value wisdom so much. I think of the most valuable thing in the world, most valuable thing that exists is wisdom. And we really have this opportunity to help preserve wisdom of elders. And eldership has been diminished in our current culture. We're not as often as interested or engaged with our elders as we once were. But part of that is because our elders aren't what they used to be either. So enabling these incredibly valuable and important people in our lives to have the longest running capacity of their brain.

Is a calling. And to grapple with this multifactorial, relentless, degenerative process.

Takes bravery on the part of all concern. It takes patience and kindness because it's a tough thing to be engaged in. So first of all, I want to say hats off to anybody who has the bravery to dive in and go for it. I would also say that I'm going to change my recommendations for you is probably every three months.

As an ideal, but that would really go upon tracking. And I think that's. We cannot take relationship out of medicine. And relationship is a longitudinal story that is shared between a patient and a physician. And that relationship should impact exactly what kind of care people deliver, how often they're getting it, and what would be the best strategies to augment that care. So it's.

I don't use the word calling lightly, but it can't be anything but because on the other side of this, it's so exciting to work with people who are peak performers and so interest, you know, individuals that are the, you know, it's the children of the individuals with neurocognitive disease that really need to be grappling with this process because you have so much more brain, so many more healthy stem cells, so much more to work with that the amount of intervention and the intensity of intervention is less than what it takes once you've had multiple common systems failure that we call dementia.

Well, that was.

Fantastic. I love how you think and I've always just loved your work. I love who you are and what you do. And I can't wait to get inside the clinic as a patient and an advocate and be able to report back what my experience is as well. Like I said, I'll be a good, compliant patient and scientific about it as well. And.

I don't have anything else except thank you very much for your time today. I'm sorry. Super excited to be working with you on another level. And also the progress of this science and work is important and valuable. I think there's a lot of people whose lives can be changed and a lot of pain can be prevented along the way for both people going through it, but more importantly for the families who are witnessing it because it's harder for them than it is for the person going through it who, chances are, is oblivious. Right.

So, well, that's what we have. So to learn more. And did you have one more thing to say?

Well, I just want to say again that, yeah, you're absolutely right.

It is.

The burden really falls on the family because when you're working with someone with cognitive decline, they become less and less capable of doing this action themselves. It does take that advocacy and that relationship. And you're so right.

It is.

And.

And I want to give kudos to anybody who looks at this in the face and takes it on. I have huge respect. And Mike, thank you very much for having me on. Thanks. I love this podcast. It's one of the few that I think I have listened to every episode of this particular podcast. It's just.

Dan has been quite a mentor of mine. I'll tell you, Strategic coach as a organization is so top notch and he has changed the quality of my thinking and the quality of my life. So I have a huge amount of respect for both of you and how you seek to amplify people's capabilities. So I hope that's what we've done here today and not just amplified, but extended their capabilities.

Yeah, that's true capability. Except extender. Well, with that, thank you, Dr. David Hazy. You can learn more about him again by heading to his website@maxwellclinic.com you'll learn more about everything he's up to and also an opportunity to get inside and try out the program like I'm about to. So thank you so much for watching. This is Capability Amplifier.

Sam.