345: How to Effectively Use Intermittent Fasting with Cynthia Thurlow

5 Dec 2025 · 35 min
Episode

5 Dec 2025 · 35 min

0:00

Podcast interview (Natalie Jill with Cynthia Thurlow) about intermittent fasting for midlife women. Cynthia defines fasting simply as "eating less often," recommends women aim for a 6–8 hour feeding window with at least two meals (to preserve lean muscle and insulin sensitivity), emphasizes protein (working toward ~100 g/day), and discusses mechanisms (insulin sensitivity, blood sugar spikes, chronic cortisol/stress, autophagy, gut repair). Practical guidance includes: start by removing snacks, gradually lengthen the overnight fast (water, bitter teas, coffee, electrolytes allowed), consider carb-cycling around activity, use CGMs/glucometers to personalize responses (aim for ~20–25 point post-meal glucose rise), and monitor fasting insulin (an inexpensive early biomarker). Benefits cited: improved mental clarity, better sleep, improved lipids/blood pressure, lower risk of some cancers and neurodegenerative disease, and greater food freedom.

Questions this episode answers

A 6–8 hour feeding window with at least two meals.

About 100 grams of protein per day.

Fasting insulin; she notes it typically costs about $12–$20 and is inexpensive/covered by insurance.

About a 20–25 point increase on a glucometer/CGM.

About 200–300 grams of carbohydrate per day.

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