412: Reversing Skin Aging: The Science Behind Peptides with Alessandra Lead Scientist at OneSkin

I think like the best is the combination of both. It's not that topical does not work, but it's not also all that you eat will work by itself. If you do only one and don't do both a little bit right, you kind of like you're not working holistic on your body and you will not have the best results on the best result comes when you're doing both approaches.

Hi, I want to welcome you to Midlife Conversations. I'm Natalie Jill, your host and I help midlife women redefine and rebrand aging. On this podcast, I do what I do best, taking complicated in information and conversations around aging that are relevant to us now and breaking it all down simply with actionable steps that you can implement to level up your life because.

Your best years are yet to come.

I also regularly interview some of the most inspiring people living in their best midlife years. On this show I cover topics about our health, hormones, navigating weight, blood sugars, our mood, focus changes, even our relationships, career changes, beauty, and more.

Today we're talking about skin and how it changes as we age. And me at 53 at the time of recording this, is very aware of the skin changes. I thought I had this down. I thought I understood. And even though I regretted sun exposure when I was younger, I thought I'd been taking really good care of my skin, wearing a hat, using mineral based sunblock. But those little brown spots start to show up, those thin, those little lines, especially as our hormones start to change. And before we even get into my guest today and watch, I want to have her on I am on hrt. I'm doing hormone replacement. I'm using, I was using an amazing skincare regimen, but I was still seeing a lot of those signs of aging. So one of these burning questions I have had and I've asked my audience and I've asked many of you listening, what do you actually recommend for skin and can we actually truly reverse the signs of aging? And do we have to use a lot of gadgets and a ton of product or is there really something that can contribute to changing the way that our skin ages? I've tried a ton of products. Lots of things have been sent to me. I've tried oils, I've used light. I've done all the things and I love all of them. They all contribute. But there is a product that I recently started experimenting with that has actually changed the way my skin feels and I'm starting to see how it's shifting the way that it looks. So Today I'm really excited to introduce to introduce Alessandro to midlife conversations today.

Alessandra to midlife conversations today. She is the chief scientific officer of One Skin. Now the reason I wanted to dive into this topic is one skin is a topical peptide, a proprietary OSO1 peptide. And I have a lot of questions for her on how she discovered this, how it actually works, some of the results she's seeing and it who should be using this and when should we start using it. So thank you so much for being here today.

Thank you so much, Natalie, for having me. I'm so excited for diving into all this conversation.

So let's back up a minute. How did this even become a topic to you? Because just looking at you, your skin looks phenomenal. I mean, you are a walking advertisement yourself. I asked her age at the beginning of this and she is on the younger side of midlife. She's 37. But we're not basing this just on her phenomenal skin. I want to hear how you even fell into this and why you got so interested in this.

Yes, definitely. So I would start from the beginning and as you can see from my accent and my name, I'm not from the U.S. i'm from Brazil originally. I was born and raised in Brazil and from a young age I was always fascinated about science. I wanted to find a cure for cancer. I wanted to clone my family so I would never lose them. I had all those ideas when I was like 10, 12, 13 years. And then I pursue, I went to college and I started studying biology and I knew I wanted to study stem cells and how to grow organs in the lab. So I never thought at that age that I would be like leading the science of a beauty company. But I always wanted to do something. I was always interested in real science and things that can help people life. So throughout like after college, my master and my PhD, I was specializing on stem cells and tissue engine grow organs in the lab. And my PhD specifically I was interested on skin wound healing. So I was studying how to associate stem cells with biomaterials to promote better wound healing. And I did this throughout my PhD and eventually even after my PhD I moved to Portugal and I continue my research and studies on wound healing and how like to improve scar tissue. And then in 2017 I I had some colleagues from Brazil that were doing the finishing. They had finished their PhD on the same lab that I also like researching stem cells. Three other female scientists eager to do something that could be translated to people's life. So one of Them Carolina had moved to San Francisco to start the idea of one skin in a accelerator program that they have here in San Francisco. And then she called me, invited me to join this early team and to lead the science of this new company which the goal was not yet to have a product, but to understand skin aging, the importance of skin aging and the biomarkers of skin aging. And at the end to validate like in this crowded market like what really works or not.

Yeah, yeah. It's confusing because we don't, we don't understand. And I want to start with. I think the go to with anti aging or aging reversing the way that skin ages has been Retin A and hydroquinone. If I'm pronouncing. Pronouncing that correctly. And that's one of them is a bleaching cream and the other one Retin A. Do you know much about those and why and why not use those?

Yeah. So yeah. So then when we definitely when we started these are the gold standard products for skin. And if you look at them, they were like developed on the 50s, they were like found to be helping on skin aging. But they were not designed to address root causes of skin. And that was the point that started to fascinate me when we started this research is that the products are out there. They are not targeting root causes of skin aging. And the science of aging has evolved so much on other areas, but none of those science was yet applied. And then when you look like retinoids, they are inducing cell turnover. So they induce that peeling effect on the skin which leads to a better appearance looking of the skin. But does not treat what's causing skin aging. And at the same time is very. It can be very irritating, especially for those who has sensitive skin. So always had sensitive skin. And my skin was not, not always like flawless like it is right now. And I always, when I went to a dermatologist, they recommend me retinoids and I would try to use and my skin would get more red, more irritated and was such a frustrated, frustrating process. And. And then I saw myself starting to investigate this in the lab.

Yeah.

And trying to see and starting to understand that really they can give some good results. But they are not targeting what's causing skin aging. What is a driving the process of collagen loss of the weakness of dermal layer and of the. How I say melanocyte dysfunction that will likely to. To those eight spots.

So the reason I personally stopped using Retin A and hydrocun, I don't Know if I'm even pronouncing that right. I. I really liked using those. I thought that we were supposed to use them. The reason I stopped is my liver numbers changed. So I'm. I do my blood work every 90 days and I noticed I had high liver enzymes. And the only thing I could attribute it to was those two products. So I stopped using it because they do get in your system. And I thought, okay, whatever that's doing that to my liver numbers. I don't want that for my skin. So that's why I had stopped that. So I had switched to just eating collagen, red light, using some heavy oils. I liked castor oil, things like that. But then unfortunately my skin started getting not better. It started getting. Not that those aren't great things, they're great things. But I started noticing after stopping Retin A and hydroquinone, I was getting the brown spots back. I started getting more fine lines, especially above my lips. So I was excited to go dive into this, which is topical peptide. So can you explain how that works? Because I think a lot of us have been taught that topical wouldn't work. We have to eat it. It has to be part of the inside.

I think like the best is the combination of both is not that topical does not work, but it's not also all that you eat will work by itself. If you do only one and don't do both a little bit right. You kind of like you're not working holistic on your body and you will not have the best results on. The best result comes when you are doing both approaches on the best way. So the top go is very interesting when you are ingesting collagen. Yes, some collagen can like help minimizing the loss on the skin. But that collagen, it's being degradate on your intestine and the peptides, the collagen breakdown is going to. To your whole body. So it's not that it's specifically just filling the gap that is needing on the skin is overall gap when you're applying something topically. A peptide topically is acting exactly on the skin. So it's kind of like boosting the production of collagen on the skin. So the combination of using those two approaches usually is when you will get the best benefits. Because also if you only apply like good products on your skin, but you eat poorly, you don't take care of your sleep, you have bad habit habits in general, you will also like not get the results that you are looking for.

So, okay, true story here. And I'm going to ask you questions about the peptides and how this actually works. So a few months back, I had gone all natural. Like every. I was, I was sharing with my audience, like, I'm detoxing. Everything I want, all natural. Like, don't talk to me if it's not natural. Like, everything is full, fully 100% natural. So I got rid of my retin a, got rid of the hydroquinone, got rid of all my skincare products and went to straight, just oil, red light, eating collagen. Like, like, literally, that's it. I was washing my face with oil. Like, it wasn't. I was doing nothing. And my skin started actually not looking its best. Okay. And actually I had. My makeup artist was doing my makeup for something and I said to her, do you notice these little lines? Like they came out of nowhere? And she said, yes. She goes, let me ask you, did you go to all natural products? I was like, like, yeah, I did. She goes, that's what's wrong. Sometimes science is good. So I went to my esthetician and I said, I don't care what I need, but I need good products. Like, I need. Give me all the things. I just need to fix this. So almost $1,000 later, like, ridiculous. I spent like a ridiculous amount of money on just. I don't even know what she gave me. I was like, I don't even care about the ingredients. Just give it to me. So I get home and I have like eight different products. I'm doing all this stuff for a month, and I'm like, wait, this is a lot of steps. And I'm not necessarily seeing a difference yet. And I know it's a long time. And that's when I came across one skin. So I stopped doing all of that. I switched over to the cleanser, the OS, the OSO1 peptide, and the mineral block. And that's all I use now on this. And it's. And so I, I wanted to share that because I know a lot of people listening can relate to, like, you're either all natural or you're going to do all the, all the things. And there's kind of this middle ground where we could. Something a lot simpler. So let me ask you, like, why is this actually working and what is in that OSO1 peptide? Why is it called that?

Yeah, I. That. That was a awesome story. And before I answered the question, like, a lot of people goes with this idea of, like, all natural is better, but everything is chemical. Like Water is a chemical molecule and people get like afraid of, oh, the word is chemical. It's not natural, but it does not exist. This such a thing of like a chemical not being natural as well. What I always like to say, like things can be toxic and that is what you don't want. So the combination of science and novel molecules, if the research is doing done correctly, it will benefit. It will allow your skin or your cells like to, to act better. While like if you're only using oils, yeah, you are protecting your skin barrier, but you are not helping or adding anything to yourself cells that may be important. So the idea of like, oh, just not going 100 natural is the way to go. It's a little bit like.

As your experience, like it didn't work.

Take it from me, it didn't work. Going extreme made me look older period. So if you don't care about that, awesome. For me I kind of care. So I didn't, I didn't, I didn't like it. I didn't like how what I was doing to my skin to go fully 100%. So now I'm like a middle ground. And I think yours is actually a really good compromise here. So tell us what is this OSA one? What is that?

So this is a novel peptide. And the way we found this peptide is because we were researching skin aging. Why they skin, when we are getting older, produce less collagen, start having collagen breakdown, sagging, hyperpigmentation. One of the reasons why is because we start accumulated accumulating damaged cells that are cells that secrete inflammation and that contributes to this like dysfunctional tissue. Those cells, none of the ingredients on the natural products, they are not targeting those cells. Even retinol is not targeting these cells. Retinol is making your skin peel and like improve the.

It's shedding like a snake.

It's like, yeah, but. So it improves the appearance. But those senescent cells, zombie cells as we call they still present in the skin and they still secrete inflammation that's leading to the signs of age on the skin. So what we did in our research was look search specifically for a novel molecule that would switch off those damaged cells, that would reduce the burden caused by those zombie cells and reduce accumulation of that. So the end result is that when you have less of what's driving aging, you have a skin that can be funct, functioning stronger and healthier. So producing more collagen and improving the appearance of the skin. So after researching over 900 peptides, we identified the OS1 peptide, that's a novel molecule. And our research shows that reduce the inflammation of those zombie cells, improves DNA repair, meaning that makes the skin function better in avoiding to become a damaged cell. And with that this can produce more collagen, has a stronger skin barrier. And the results like when you see the application is that it's smoother with less fine lines and more firmness and elasticity.

Okay. Now I have not been using it long enough at the time of this, so I'm probably going on about two months. And I can definitely feel a difference in my skin. I can feel a difference. I don't know that I fully see it yet, but I'm also looking at my face every single day. So I'd have to do a comparison. How long does this take to. And is that like sort of what people notice first is how it feels and then the appearance or what is the process?

Yeah. So usually like you start to noticing that something's getting better. From our clinical studies, we do three month analysis after 12 weeks and then we have significant changes and measured by instruments analyzed by dermatologists that I think it's improved the appearance in terms of being firmer, more elastic.

And I feel that at two months I definitely already.

Feel that. I mean especially like here too because I've been putting it on. I've been using the whole body one too. But I definitely feel that difference. Also I noticed like, okay, you know when you put like a regular lotion on or it absorbs into your skin and you don't feel it the next day like you put it on off this one, it's almost like you just put it on, it stays on. Feels like that always. It always feels like you just put it on fresh.

Yeah. It maintains the moisture of the skin. So one data that we have very strong is like that keep the hydration of the skin. That's why you also, you have this feeling. And I love the body lotion is one of my favorite products that your skin, your whole body is just locking the moisture. And the body lotion is very interesting product because when we found this peptide and we decided at that time in 2019, we were just of scientists doing research and we identified this new molecule that we thought we would license. But then we saw better like use of the molecule if we brought this to the market and developed. So we developed first the face, the face moisturizer, the OS1 face and our second product was the body lotion. Because for us it's as important to treat your face. It's Important to treat your skin in your body not only because of the appearance, but by because of the skin for your aging. And usually especially when you are my age or younger, you always forget about your body. But later on the skin in the body start to get super thin. And when you cross like 70 years old, it starts like to tear, like to bruise more easily because of the aging process that happened on the skin that you never took care of it so totally.

I feel like even when we do think we're taking care of it, like I was thinking I was taking care of mine, it still starts showing. I would say it like around menopause you really start seeing the changes because of that drop in estrogen and things like that. It starts changing because my. Because I've always been thought I had pretty decent skin. But all of that stuff starts really showing up, at least for me in my 50s. How I know that you can change the moisture and you can change how it feels. Can you also and the even the fine lines because of that. Can you change dry brown spots or melasma?

So they are all connected. The brown spots are also starting to appear more because of like dysfunction on the skin tissue. And then the melanocytes are producing more melanin. So it's all indirectly correlated. When you like treat the root cause of what's leading to the skin aging, you kind of addressing all of the signs of.

Will not be. This approach of our peptide is not as a fast approach to reduce like dark spots. It reduce with time and helps reduce the appearance of novel spots. So we always like to see our. Our line our routine as an essential part of your skincare routine that will help your skin for the long term. But you can always associate with other techniques that can help improving the appearance a little bit more faster. Different kind of lasers or.

Red light therapy, microneedling other other things that you can do together to stimulate even more the healing process on your skin. While our peptide will be continue to avoid like that will accelerate that aging process.

Got it. Okay. When you're looking at your product line, you don't have like a lot of things which I like that it's sort of simple. How important is it to use it all together? Does it matter? Like for instance, I have your whole system. I have the body, I have the eye cream, I have the this, the face wash, I have the mineral sunblock and I have the. The peptide for the face. Like first of all, like do you. Is it important to use it all as a system? Can somebody use their own face Wash if they like. How does. How important is it to use it all together?

Yeah. So our line is basically like the essential steps that you need for like taking care of your skin. So you need to clean your skin, you need to was moisturize your skin and you need to protect from sun damage. All of our products, aside of the cleanser, the cleanser does not contain our peptide because the washout, okay. They contain our peptide. So the body one is the one that you need for your. For your whole body. Compared to the face and the face, the eye cream is more targeting when you have more signs of aging around the eye. This cream has a higher concentration of the peptide. So it's more for when your skin is more already damaged. A lot of times people also use on neck or around the mouth the.

Eye cream they'll use there. Okay.

And then you have the next step of the sunscreen. If you are using the full line, you're getting the most out of the peptide. But if you already have a different routine, this, if you add at least one product, you will already be helping your skin by adding this type of ingredient that none of our daddy products are having. And it works pretty well with other products as well. So it can be used combined. It's not essential. Like you can also like keep more simple the routine and you will find everything that you need in the combination of the these three products.

If you are using other products like let's say you love using a vitamin C or you love using your whatever your whatever your estrogen cream on your face or whatever it is. Is there a proper order? Like does this, does the peptide need to be put on first?

Yeah. So from the data, the research that we do in the lab, we always like we. We receive skin samples from leftover plastic and we treat with to analyze what is going to do to the skin or not. And from our research we always, we apply first our product because you. You get more of the absorption.

Okay.

That said, it's not that depending on the typ serum that you have before it's very thin, it will not interfere that much. Anything that is heavier, I would say to add afterwards. But it goes well with other products. And if you already have a sunscreen that you love, you can like use the, the face peptide and the sunscreen that you love on the top or.

Yours is a mineral based one. Correct.

And so I love that problem.

Can you explain that to people? Because I know there's a lot of concern about sunblocks being toxic. Like a lot of the chemicals but mineral bases, not that. Can you just speak a little into that?

Yeah. So the chemical sunscreen, there is a risk that can go to your bloodstream that they can penetrate your skin. But it's important to notice that there are some studies that shows the negative effect of using those chemical sunscreen on your systemic body. But they are. Usually the studies are done when you apply a huge amount of sunscreen like, every day. It is not what usually people do. So it's not that chemical is completely bad, but there is some risks. So that's why we decided when we were doing a sunscreen to go with mineral that's safer. Like, we decided to go with more of a safe route of a sunscreen that creates a layer that blocks the. The UV rays on top of your skin. And there is no chance, at least there's no studies showing that has any side effect, toxic effect to your body. So the.

My understanding. And I. You're the scientist, not me, but my understanding is with mineral, you're almost like, repelling, like the sun's bouncing off where the. The chemical, it's just like, kind of trapping it within. Right. So that's so. So to me, I know there's, like, a whole train of thought on, like, not using sunblock or sunblock. I'll tell you what, my face is gonna always have sunblock, and I'm always gonna wear a hat. So what? So I'm gonna go with the mineral one. And I like yours. What I also love about yours is you have two different face sunblocks that I tried. I don't typically love mineral sunblock because it's white and it makes your face white, but they have a tinted one, so it's super cool. So you put it on, and it's almost like a little light layer of foundation. So it's.

It.

Your skin just looks better from it. You don't get that white, pasty, weird glow that we see sometimes. I know. I know you've seen that with some of, like, the crazy natural sunblocks are, like, white.

Yeah, I. What I love is that we got to a formula that you almost. You don't feel that you're applying a sunscreen because it really spreads super easily. And the tinted one, it just does not leave any white cast. And we're even evolving next summer to get more deeper tones on our tinted version. And. And one other thing that I love about this sunscreen is that we also combine powerful antioxidants in the formula, so we compare to several vitamin C serum, and we have like the same or even higher than a vitamin C serum.

Wow.

Can even like skip this step of the serum by using our. Our sunscreen.

Oh wow. I didn't even know that. So that's awesome. Okay. Yeah. I definitely have minimized like I bought all that stuff, the other stuff and I'm like, why did I all these steps and I'm like, this is like way simpler. This is like this is easier. Yeah.

For me I'm very practical person. I always liked for things more simple. And that's the goal of One Skin. One Skin wants to provide gentle, simple and effective products. So it's not our goal to complicate but to. To bring the essential products that you need to keep your skin healthier. And if you want to complement with others. Some people love to use. They like the routine. They. They are used to have like those long steps. That's okay as well. You. Yeah. It's a very safe to be combined with that.

Not me. When I'm tired and ready for bed, I'm like, I want to go to bed. I want to just wash my face, put some quick thing on and go to sleep. I don't want to do 20 steps at night.

That's me.

Yeah. No, this is. This is great. How so? When you talk about this peptide, this OSO one. Is that your unique peptide? Is this another. Is this something that. Because like a lot of people listening also go to their doctor and get peptide injections and things like that. Is that something that could also be done that way?

No. This peptide is proprietary by One Skin. So after we discovered we. We own a patent on this.

Okay.

And its application so far is only described for topical applications.

Topical.

Yeah, they. I mean in theory and we. We thought in the beginning of exploring like more intravenous application applied and all the power that this could lead. But because the novel molecule to go to all that route, it needs a lot of study on safety before anyone starts acting this peptide and then would just like change move the focus of the company. We are a small company so we decided to focus. We want to get and we do see benefits on topical application. So that's where we want to be.

How many people or who is ideal for this to help. And I'm asking this because I have listeners that have like deep wrinkles right now. They really have their skin is not what they want. It's been years of this declining. Is there hope for reversing that with this? Yes, like real hope like or what to help me.

Any like independence on the journey where you are in the journey. This product will. You will have benefits because it's targeting some of the root cause of aging and is slowing down the accelerating this aging process. It can also reverse a little bit. And we measured this in the lab that the. Because you slow down those damaged cells, you reverse the biological age of the skin. But there is a limitation to the power of how much this can do. So if you are like on your 70s, 80s, with a skin that's already deeply wrinkled, this product will still benefit you. You feel your skin healthier and a little bit stronger will reduce a little bit the appearance, but it will not make your skin okay.

Thank you for being honest with that. Because it's very hard for us to see this. When we see advertising, we're like, you know, not with you guys, but. But in general we see ads and it's like, it's hard to know what to believe, what not to believe. What about the woman in her 50s, like, so me, for example, I'm starting to see like the starting of it. Is that ideal for this?

This is ideal. Like this point when you are starting to see the visible signs of aging and you're seeing the changes that's happening on your skin is actually a good time to start. Because what is happening is changes in your hormonal levels, but they are also being influenced by those damaged cells. They start like to their damage start to show up more. So when you minimize that, you're definitely helping your skin to become healthier, stronger, and to accelerate this aging process on your skin.

And just to make sure I'm clearly and clearly understand you, you can use it with other products, but do you put it on first? Like, should this be the first thing you put on after washing your face?

We prefer to be. To ensure more absorption of. But if you use as a second layer, you still see benefits. But we always like you want to take the most put it as first. And if during the day you want to add something else, at least at night, like put it at the first step to okay more.

What about someone younger? So like we're talking like 30s, 20s, like they're like, do you recommend they start this before there's issues?

This I think the earlier you start, it's always preventing is always easier than reversing. So the earlier, I would say after 20, end of 20s, you start already seeing some changes on the skin. Beginning of 30s, the middle 30s. So when you start earlier, kind of avoid to have damage later on. So the earlier you start, even if it's okay, the the sunscreen, you don't need to add all these steps, but add at least one to it.

Yeah.

Your skin will be grateful some years later.

What any downside that we need to be aware of anything that this is anyone that this is not for or any risk or like, hey, if you have this diagnosis, you don't want it anything like that.

I mean, we always want to apply like on the skin that is healthy. There is no like damage or open wounds on the skin. But the way we, we develop all our formulas and I'm very proud of it, we are very careful on the safety side. We run a lot of like, studies in our lab testing on skin to make sure that there is no side effect. Our products, they are fragrance free and we run tests for sensitization and allergies. So it's very safe for sensitivity.

So hypoallergenic, basically. Like, yeah.

We, we recently we got the certification from the National Eczema foundation for all our products. So they are safe for sensitive skin.

Okay. Any.

One, like if someone has autoimmune or still, you're still okay with this? As long as there's not open wounds. Okay. So no issues with that. What about this has just happened to me. I was super frustrated because I've been, been really committed to, like, I want to use this for three months and like really see the difference. And then I was traveling and I didn't bring both trips. I forgot it for a week. So what happens in those cases, like, you're using it daily and then you don't use it for a week. Is that gonna do? Are you starting all over?

It's not that you're starting all over. Like, you're always, you have a breakdown of one week and you come back, your skin will still, it's, it's still on the benefits.

Okay.

You stop like for three months, for two months, you're gonna miss that more. But like a one week or if you do alternate, like forgot one day.

Yeah. Needs to be like, Alessandra, you have like, I mean, you're just, your skin looks like perfect to me. Like she, you guys, if you're watching her on video, it doesn't, it looks like she doesn't have a drop of makeup and she just has this like perfect porcelain, amazing skin. What other tips do you have for us? Talk to us.

I mean, I mentioned to you earlier and I feel, it feels a little bit biased to say, but I, I, I can send picture of me four years ago before starting. I always had so much problem with my Skin was always super reactive, was always like getting red burning. And today to receive compliments on my skin I always feel like wow. Because I never thought okay happen. So the really change. The. The change that was big for me on these past years was slowing down on excess of products and keeping more simple with the things that are effective. And this helped a lot my skin. But coincidentally like on this process of building this company very focused on longevity. I really changed a lot of my habits, style. I'm a person, I exercise daily. I take care of my diet, avoiding like processed food and excess of sugar.

And I also take care a lot of my sleep. So I think all of that it's the kind of the basics but sometimes we never done do it correctly. But I feel that today Even though I'm 37, I have more energy than when I had 27. You know, you feel that your body is just at the performing at the best. And I don't have many, many, many hacks. I keep it simple to the basic.

And like do you use red light.

Or anything like that too or. No too.

I. I not use frequently that frequently. Red light is something that I want to. I do once every three months or something like.

But not like a day. It's not a daily thing. And your skin looks.

No, it's not a daily thing yet. Yeah. Yeah. Not.

Yeah. So do you have like. I'm. I know you study skin and you're, you are the scientists here. Like you do. Are there any like, like success stories that stand out that we should hear about? Like they. I wanna, I'm just curious about the woman that like was. Hated her skin or was trying like any of those that stand out in your mind that you know that you're, you're grateful you do what you do because of that, that.

I mean I, I do for me like on this process of building one skin, I saw the benefits for me to my skin when I see for instance our body lotion has so many reviews of people that crepess skin that couldn't wear shorts anymore that were like a. Of using like short sleeves and they just like oh the, the skin on my upper arm is so much better now. The skin around my knee. I'm using shorts again. All those stories or even like more thin skin that bruise a lot and they just like have the reviews that the skin is not bruising that much. It's feeling more healthier. This motivates me so much inspired. And also there's also the other ones like improve the appearance of the skin but when you see that improve the function of like, the skin is really like, like totally. We receive a lot of those reviews and they always like, enlighten the whole team. I love that we're just like, okay, we're doing the right thing.

You are. I will share that. When I, before I ever tried your product, I had put, I had done like a reel on Instagram and I was just. Or was a picture a real. I don't remember. But I was sharing that I had moved from California to Arizona and it's super dry here and I was asking my, my audience for advice. I'm like, okay. One of the things I asked was, what can I do for skin? Like, my skin feels dry and I've got the brown spots and I've got the aging. Like, what do you guys recommend? And I was, I was literally asking, like, what do they recommend? And so many people wrote One Skin. And I was like, wait a minute, like there's something to this. So I saw that on my own just from asking that question. And this was not like influencers telling me or anything like that. Like, I, I saw people's comments. So that's when I started trying it and I, and then I ended up making a reel about it because I was like, this is, this is freaking awesome. This is definitely making a difference. So I will report back to everybody because I am in the. It sounds like I'm almost to that three months. I still have another like few weeks to really go to see a difference. I wish I had taken better like close up pictures before and after because I want to compare, but I'm loving it.

The pictures to compare. Sometimes we forget.

But yeah, and I'm definitely going to be a client for life here because I really like it and I especially love your sunblock and all things. Well, this is so helpful. Any other things you want my women to know about aging or any advice that you want them to know about skin? And what are some final things about One Skin? Which by the way, before she answers that if you go to One Skin Co, One Skin Co Natalie Jill, you'll find all the stuff that I use there. And I believe if you use code, Natalie Jill, if it's not already built on that page, if you end up on their site a different way, that helps you get a little bit of a discount there. So. But One Skin, dot co Ford slash Natalie Jill. All right, tell us what you want. What do you want them to know?

Okay. I think like the message that I want to share is that improving the Appearance of the skin is, yes, is important make us feel good about our skin. But just remember that the skin is an organ, is a vital organ that we need to, to keep it functioning well. So it will help our body throughout aging. So treating your skin like to a better, strong skin barrier, it's actually like protecting your internal body on this process of a really good. This is something that people don't realize that much that there is a connection and like keeping, maintaining, taking care of your skin early on and throughout the life. Because what lead us to after 65 years old to be more susceptible for chronic diseases is an increase of inflammation in our body.

Wow.

The skin, because the large organ is contributing to this level of inflammation that's increasing in our body. So when we take care of our skin and we reduce this burden of inflammation throughout life, we are actually like working on a stronger body that will be more helpful for you later on in life and will help reduce the burden of inflammation on your body as well. So there's a lot of relation of the treating your skin not only for the appearance but to really to keep your, your body better and more healthier later on in life.

So if you're listening to this too and you've had some good experiences with this, please let us know whether you're watching it on YouTube. Comment under the video. I'd love to see that. If you're listening on the podc, I guess you can. Well don't put it there probably on the under the podcast, but you can send me a. Send me a direct message. Send one skin direct message. Just curious. I'm actually really curious your feedback. I'd love to hear this. This is all new to me about topical peptides and this product and I, and I do love it right now. So I think it's. This is great. I feel like I found my happy medium with you know, going all toxic or being like fully naturally. This is, this is the, this is that thing that's working for me and it's super simple. Thank you so much for being here today, Alessandra.

Thank you so much, Natalie.

I hope you enjoyed the episode.

Thanks for taking time out of your.

Day to listen in as my guest. If you found this episode valuable, please share it with friends and on social media. Be sure to tag me and our guests so that we can find you and share the love. I'm Natalie Jill Fit on all social media platforms and the biggest thank you that you can give me is leaving a review and hopefully a nice one at that. This will help other others find these episodes, we can help and reach more people. If you do leave me a review, please Message us@supportnataliejillfitness.com with a screenshot of your review and we would love to send you a free digital download of my DSR journal as a thank you.