Robert Whitfield MD and another clinician discuss research from the Breast Implant Health Summit. Dr. Sina's work links bacterial contamination and biofilm to oxylipins that may drive progressive symptoms. Genetic differences likely explain why some patients get only local issues while others develop systemic symptoms like numbness, fatigue, and brain fog.
Now, we were on a call a month ago, I guess it was now for the Breast Implant Health Summit. And we discussed Dr. Sina's paper, which I still feel like it's the best paper going in terms of explanation regarding cause and effect between bacterial contamination, biofilm interaction between the breast tissue and then formation of oxylipin tin home, which creates more and more symptoms. So maybe, and maybe it would be good for the audience to understand, like how you used to think about it and the progression now with more available evidence. Because I was really impressed by the amount of evidence put forth on that call, like you wore that we were on. It'll help the patients better understand the problem as well.
Because the reason I got interested in genetics is because I realized that patients present problems, symptoms quite variably among the different people. Because I think the only way to explain it would be genetics. Because we do have patients that have a rupture, that only have local symptoms. And I really try to differentiate between local versus systemic. But if you have numbness and tingling in the feet, fatigue, brain fog, those probably will be systemic.
