Dr. Robert Whitfield breaks down the Larsen study on capsular contracture: 51 samples started, 48 made it through RNA sequencing, and only 44 remained after removing outliers. Each quality-control step shrinks the dataset and limits how much you can trust the results.
Here's an important denominator check. The Larsen study began with 51 samples from 50 women. RNA sequencing was performed on 48 samples, and after 4 outliers were removed, the final transcriptomic analysis appears to include 44 samples. Those numbers represent different stages, so we should not blend them together. Quality control can be appropriate, but it also affects how we confidently generalize about the data. I'll walk you through the findings. Thursday at 6 PM Central, 7 PM Eastern. This is educational only. Join Dr. Rob's circle. It's free to join. Go there and sign up.
