MS misdiagnosis in two academic referral clinics

24 Oct 2026 · 1 min
0:49

In this brief YouTube presentation, Dr. Robert Whitfield reports findings from two academic multiple sclerosis (MS) referral clinics, where 17% and 19% of patients referred with an existing MS diagnosis were later judged to be misdiagnosed. He clarifies that these referral cohorts are not representative of all MS patients. He then describes a separate series of about 110 patients who had already been misdiagnosed with MS; the most common alternative explanations were migraine, fibromyalgia, nonspecific symptoms accompanied by abnormal MRI findings, and functional disorders such as neuromyelitis optica spectrum disorder (NMOSD). Lyme disease appeared on a longer list of infectious causes but was not a leading diagnosis. Dr. Whitfield emphasizes that while most MS diagnoses are correct, strict adherence to diagnostic criteria, consideration of clinical context, and careful re‑evaluation are essential. He invites viewers to a free livestream, with sign‑up details provided in the post.

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