Mast cells throughout your body can become hyperactive when exposed to implants, infections, or chemicals, releasing inflammatory mediators that cause problems wherever they're located. The gut and nervous system are common trouble spots because they have large surface areas exposed to the environment.
they get implants or they get exposed to some major infection or they get exposed to an environmental chemical. And those mast cells, which were already abnormal and already ready to fight, they fight really hard and they fight and they release all these mediators, these chemicals that are really inflammatory and wherever they're being released, they're gonna cause a problem. But they're everywhere in the body. They're literally every— they're in the veins, they're in the arteries, they're in their digestive system, they're in the respiratory system, they're in the skin. And so really, and the genitourinary system, the uterus, the bladder, the vagina.
Is there a particular system that has a higher concentration or organ
system? Not that we know of. And I think it may differ from patient to patient. But basically, anything that's an interface with the environment is gonna have a lot of mast cells.
The surface area of the gut is gonna be, outside of the skin, probably the largest surface area.
Probably. I mean, I would guess that that's true. And which is why we see a lot of gut issues, which we can talk about. The nervous system is the other place.
