Danish research shows scar tissue around medical implants triggers an immune response similar to organ rejection, activating B cells and antibody production. Scientists are developing an RNA test to detect this early immune activity in tissue samples, potentially guiding when anti-rejection drugs are needed.
The final and more interesting component was published recently in a paper out of Denmark and showed that the tissue, the scar tissue around the implant that the patient produces is acting in a way like it's rejecting an organ. Hmm. So it's increasing. Not just a T cell response, which is normal. Yeah, it's causing a B cell response and a plasma cell response. Okay, so if, if, you know, I were to donate a kidney to Betty and our blood types match, that would be the first level of match. Right. Second would be the HLA match. And if it was a negative cross match, then she could have the kidney. But she would need drugs to prevent what I just said. Yeah, like a cell sub kind of.
Anti rejection drug.
You're going to create antibody, you're going to create a rejection. And that is what they're seeing now. And so that, you know, imagine someday I can do an RNA test, because that's a transcriptome test. They're looking at rna. And so if I could just send off a piece of tissue and get an RNA transcriptome analysis, wouldn't that be nice?
