The Secret Drug That The Stars Are Using To Get In Shape (#406)

13 Jan 2023 · 65 min
1:05:08

In this episode of The Hustle Show, hosts Sean O'Brien and Sam Parr discuss the rise of semaglutide‑class weight‑loss drugs such as Ozempic and Wegovy. They explain how the drugs work, their side‑effects, and why they have become a cultural phenomenon among celebrities and fitness influencers. The conversation shifts to the ethical dilemma of drug shortages that leave diabetic patients without access, and to the lucrative business ecosystem that has sprung up around GLP‑1 therapies, including affiliate programs, subscription services like Calibrate, and Sam’s own bio‑hacking experiments (semaglutide, BPC‑157, vaping). They describe how they track emerging trends on Reddit and niche forums. The hosts also touch on related tech and pop‑culture topics: deep‑fake visual effects from the company Deep Voodoo, Kendrick Lamar’s music video that employed the tech, and a brief nod to the creators of South Park. The latter half of the episode becomes a personal “bro‑session” where Sam reveals his ambitious financial goals (aiming for a $150 million net‑worth by age 40), his desire to own multiple property compounds, and his philosophy of setting extreme masculine goals (bench‑pressing 300 lb, being a “fucking man”). Sean jokes about Andrew Tate and the hosts reflect on the tension between confidence‑driven goal‑setting and the potential for toxic masculinity. The episode ends with a self‑aware apology to their female listeners and a meta‑commentary on the podcast’s tone.

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