A brief YouTube short by a 39-year-old board-certified dermatologist describing her personal melasma experience and explaining that treating melasma/hyperpigmentation requires a multi-ingredient, multi-checkpoint approach. She outlines three main pigment-pathway checkpoints to target: melanocyte activity, tyrosinase-mediated melanin synthesis, and melanosome formation/distribution.
Chapters
A 39 year old board certified dermatologist and let me tell you, I've had my own struggles with melasma and hyperpigmentation. This is me at the height of my melasma flare up when I was not using a consistent routine targeting the pigment pathway. The fact of the matter is when you're dealing with melasma or hyperpigmentation it is not a single ingredient story, not even vitamin C. There is no one stop shop because you have to hit the pigment pathway and how pigment is produced at various different checkpoints. Let's get into it in a very simplified fashion. It's a multi ingredient story because you have to target the pigment pathway at different checkpoints starting with the melanocyte, the cell itself that produces pigment. You can shut that baby down. Within the melanocyte, melanin gets made. That checkpoint can also be shut down through tyrosinase inhibitors. Once the melanin is made it gets put into tiny little parcels also known as melanosomes and these melanosomes then get distributed throughout your skin which is another checkpoint which can be targeted as well as.