Shereene IdrissBoard Certified Derm, Founder and Chief Nerd

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30 Jan 2026 · 0 min

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Shereene Idriss explains how to use retinol without irritation: start with 2-3 times per week, then apply zinc-oxide diaper-rash cream on off nights to let your skin heal.

Questions this video answers

Two times a week or three times a week at most (2–3 times per week).

A zinc-oxide diaper-rash-style cream (used as a face-basting/slugging treatment).

But if you are somebody who does not necessarily tolerate a retinol every single night, you can be consistent on a weekly basis like two times a week or three times a week at most. Then using a zinc oxide diaper rash cream on your off nights can work miracles to help heal your skin more effectively. So if you have any questions or comments or concerns as always, leave them below and I will get back to you.